101-99-5Relevant academic research and scientific papers
[2+2] and [2+4] type cycloadditions of isocyanates with ynolates
Shindo, Mitsuru,Harada, Akiko,Matsumoto, Kenji,Shishido, Kozo
, p. 39 - 43 (2005)
Ynolates react with isocyanates to give azetidine-2,4-diones via a [2+2] type cycloaddition. The [4+2] type cycloaddition proceeds in the reactions of vinyl isocyanates with ynolates to provide 2-pyridones.
Preparation and applications of a polymer-supported phosphoryl azide
Lu, Yuhua,Taylor, Richard T.
, p. 9267 - 9269 (2003)
A polymer-supported diphenylphosphoryl azide was prepared. This polymer-supported version of DPPA is useful due to its lower toxicity, moisture tolerance and ease of workup after reaction. The synthetic application of this solid-phase reagent was explored by conversion of a variety of carboxylic acids to urethanes and ureas through Curtius rearrangement reactions. Carboxylic acids bearing different functional groups (aromatic, aliphatic and heterocyclic carboxylic acids) were subjected to the reaction. The corresponding products were isolated with satisfactory yields.
Ultrasound promoted 'one pot' conversion of nitrocompounds to carbamates
Chandrasekhar,Narsihmulu,Jagadeshwar
, p. 771 - 772 (2002)
An efficient ultrasound promoted novel direct conversion of nitro compounds to N-(tert-butoxycarbonyl) amines and N-(ethoxycarbonylamines) is achieved using Sn-NH4Cl for the first time.
Chemistry and antioxidant properties of titanium(IV) complexes
Shaikh, Zara,Ashiq, Uzma,Jamal, Rifat Ara,Mahroof-Tahir, Mohammad,Shamshad, Bushra,Sultan, Sadaf
, p. 665 - 671 (2015)
Abstract The synthesis of titanium(IV) complexes with biologically active hydrazide ligands has been carried out. The complexes were characterized by spectroscopic methods (IR, 1H NMR and 13C NMR), elemental analysis and conductivity studies. These studies suggest bidentate coordination of the ligands through carbonyl oxygen and primary amine nitrogen, resulting in octahedral geometries. Hydrazides with pyridyl substituents displayed 1:2 metal-to-ligand ratio, and hydrazides with imino substituents exhibited 1:3 metal-to-ligand ratio resulting in an outer sphere complex. The remaining complexes displayed inner sphere coordination with 1:1 metal-to-ligand ratio. These complexes exhibit varying degrees of radical scavenging properties against DPPH, superoxide and nitric oxide free radicals. The free ligands showed inhibition against DPPH but were inactive against superoxide and nitric oxide free radicals. The structure-activity relationships of the complexes are discussed.
THE PLATINUM COMPLEX CATALYZED REDUCTIVE CARBONYLATION OF NITROARENE TO URETHANE
Watanabe, Yoshihisa,Tsuji, Yasushi,Suzuki, Naoki
, p. 105 - 106 (1982)
The reductive carbonylation of nitrobenzene to an urethane (ethyl phenylcarbamate) is catalyzed by platinum(II)-tin(IV) systems.The catalytic activities are drastically enhanced by addition of a tertiary amine.
Synthesis of Amines, Carbamates and Amides by Multi-Step Continuous Flow Synthesis
Sagandira, Cloudius R.,Watts, Paul
, p. 6554 - 6565 (2017)
We report the continuous flow synthesis of acyl azides in various continuous flow systems and demonstrate that liquid–liquid separation may be incorporated to prepare anhydrous solutions of the acyl azide, which may be subsequently reacted with appropriate nucleophiles to prepare amines, carbamates and amides within a fully integrated multi-step process in high yields (> 80 %). Interesting effects were also observed when preparing carbamates with long chain alcohols, whereby as the chain length of the alcohol increased the products could be made in high yield even without incorporation of the liquid–liquid separation module.
Selenium-catalyzed oxidative carbonylation of aniline and alcohols to n-phenylcarbamates
Zhang, Xiaopeng,Jing, Huanzhi,Zhang, Guisheng
, p. 1614 - 1624 (2010)
A facile one-pot, phosgene-free synthesis of N-phenylcarbamates is demonstrated. Catalyzed by selenium, oxidative carbonylation of aniline with alcohols in the presence of carbon monoxide and oxygen affords the corresponding N-phenylcarbamates, mostly in fair to good yields. Selenium can be easily recovered because of its phase-transfer catalysis function. Copyright
Electrochemical activation of carbon dioxide: Synthesis of carbamates
Casadei, Maria A.,Inesi, Achille,Moracci, Franco Micheletti,Rossi, Leucio
, p. 2575 - 2576 (1996)
Electrochemically activated CO2 reacts with amines and EtI under mild reaction conditions affording the corresponding carbamates in high to excellent yields.
Cs2CO3 or CaO as promoters of ethyl N-{[(4-methylphenyl)sulphonyl]oxy}carbamate in amination reactions
Barani, Marco,Fioravanti, Stefania,Pellacani, Lucio,Tardella, Paolo A.
, p. 11235 - 11238 (1994)
Replacing triethylamine by heterogeneous inorganic bases makes it possible to aminate benzene or other nitrene acceptors, using the title reagent, previously reported to be scarcely reactive. Products of C-H insertion and/or those coming from intermediate aziridines are also obtained.
Improved amination by ethyl n-(4-nitrophenyl)sulphonyloxy carbamate in the presence of inorganic oxides or carbonates
Barani, Marco,Fioravanti, Stefania,Antonietta Loreto,Pellacani, Lucio,Tardella, Paolo A.
, p. 3829 - 3834 (1994)
Inorganic solid bases give rise to α-elimination reactions of NsONHCO2Et under easy and mild conditions without catalyst or ultrasounds. For several kinds of substrates, a comparison of yields and reaction times with previous methods is presented.
