43012-47-1Relevant academic research and scientific papers
1,3-Dipolar Cycloaddition of 3-Amino Oxindole-Based Azomethine Ylides and O-Vinylphosphonylated Salicylaldehydes for Diastereoselective Synthesis of Oxindole Spiro-P, N-polycyclic Heterocycles
Huang, Tiao,Kong, Dulin,Liu, Li,Wang, Qinghe,Wu, Mingshu
, p. 1387 - 1397 (2020)
An efficient stereoselective assembly strategy for the construction of pyrrolidin-2,3′-oxindole cis-fused phosphadihydrocoumarins was established. The process involves the condensation of O-vinylphosphonylated salicylaldehydes and 3-amino oxindoles followed by intermolecular cycloaddition with high diastereoselectivity and atom economy.
2-oxoindoline derivative
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, (2008/06/13)
Disclosed is a 2-oxoindoline derivative represented by the formula (I): STR1 wherein Ring A represents a benzene ring which is substituted in the 5-position or 6-position by a lower alkyl group or lower alkoxy group, R1 represents a phenyl group which is substituted by a halogen atom, a lower alkyl group or a lower alkoxy group, R2 represents a naphthyl group, indolyl group, isoquinolyl group, benzimidazolyl group or a group represented by the formula: STR2 wherein n represents 1 or 2, R3 represents a lower alkyl group which is substituted by a carboxyl group, a cyano group or a tetrazolyl group, O represents a single bonding arm, and Y represents a single bonding arm, or a pharmaceutically acceptable salt thereof.
