43029-40-9

Upstream product

• 13229-03-3 2-hydrazino-5-phenyl-1,3,4-thiadiazole 
• 98-88-4 benzoyl chloride 
• 20939-15-5 3-methyl-4-amino-5-mercapto-1,2,4-triazole 
• 20939-15-5 4-amino-5-methyl-2,4-dihydro-[1,2,4]triazole-3-thione 
• 100-47-0 benzonitrile 
• 65-85-0 benzoic acid 
• 108483-89-2 N'-(phenyl-[1,3,4]thiadiazol-2-yl)-acetohydrazonic acid ethyl ester 

Relevant academic research and scientific papers

Microwave-enhanced reactions of 4-amino-5-merecapto-1,2,4-triazoles with benzoyl chloride and aromatic aldehydes

The microwave-enhanced reactions of 4-amino-5-mercapto-3-substituent-1,2,4- triazoles with benzoyl chloride or arylaldehydes under solvent-free conditions without catalyst were studied. 3-Substituded-6-phenyl-1,2,4-triazolo[3,4-b]-1,3, 4-thiadiazoles were

3,6-disubstituted 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles: Synthesis, antimicrobial and antiviral activity. II

A series of novel 3,6-disubstituted 1,2,4-triazolo[3,4-b] [1,3,4]thiadiazole derivatives was prepared and tested to evaluate their antimycotic and antibacterial activities. Anti-HIV-1 activity has also been investigated. Among the test compounds, derivatives 10a-14a and 16c showed anti-HIV-1 activity at concentrations slightly below those cytotoxic. Substitutions at 3 and 6 positions seems to be important in lowering the cytotoxicity of compounds.

Synthesis of 2-amino-5-aryl-1,3,4-thiadiazoles and their condensed analogs with the use of aromatic nitriles

Aromatic nitriles are found to readily react with thiosemicarzide and 4-amino-3-methyl-1,2,4-triazol-5-thione in a solution of polyphosphoric acid to give corresponding 2-amino-5-aryl-1,3,4-thiadiazoles. - Keywords: aromatic nitriles, polyphosphoric acid,