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1H-Indole-2-carboxylic acid, 5-hydroxy-6-methoxy-, methyl ester is a complex organic compound with the chemical formula C12H13NO4. It is derived from the indole family, which is a group of heterocyclic aromatic organic compounds. This specific compound features a hydroxyl group at the 5th position, a methoxy group at the 6th position, and a methyl ester group at the 2nd position of the indole ring. It is known for its potential applications in pharmaceuticals and as an intermediate in the synthesis of various biologically active compounds. The compound's structure and functional groups contribute to its unique chemical properties and reactivity, making it a valuable component in the development of new drugs and other chemical products.

4305-32-2

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4305-32-2 Usage

Chemical class

1H-Indole-2-carboxylic acid, 5-hydroxy-6-methoxy-, methyl ester belongs to the indole class of chemical compounds.

Natural occurrence

1H-Indole-2-carboxylic acid, 5-hydroxy-6-methoxy-, methyl ester is commonly found in various natural sources such as plants and fungi.

Pharmaceutical applications

It has been studied for its potential pharmaceutical applications, particularly in the field of medicinal chemistry and drug development.

Bioactive properties

The unique structural properties of 1H-Indole-2-carboxylic acid, 5-hydroxy-6-methoxy-, methyl ester make it a promising candidate for the synthesis of novel bioactive compounds with various biological activities, including antioxidant, anti-inflammatory, and anticancer properties.

Lipophilic properties

The methyl ester form of 1H-Indole-2-carboxylic acid, 5-hydroxy-6-methoxy-, methyl ester enhances its lipophilic properties, which can improve its bioavailability and pharmacokinetic profile in drug formulations.

Research and development potential

1H-Indole-2-carboxylic acid, 5-hydroxy-6-methoxy-, methyl ester holds potential for further research and development in the pharmaceutical industry.

Check Digit Verification of cas no

The CAS Registry Mumber 4305-32-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,0 and 5 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 4305-32:
(6*4)+(5*3)+(4*0)+(3*5)+(2*3)+(1*2)=62
62 % 10 = 2
So 4305-32-2 is a valid CAS Registry Number.

4305-32-2Upstream product

4305-32-2Relevant academic research and scientific papers

A Bioinspired Synthesis of Polyfunctional Indoles

Huang, Zheng,Kwon, Ohhyeon,Huang, Haiyan,Fadli, Aziz,Marat, Xavier,Moreau, Magali,Lumb, Jean-Philip

supporting information, p. 11963 - 11967 (2018/09/11)

Polyfunctional indoles bearing substituents at C5 and C6 are prevalent in natural products, pharmaceuticals, agrochemicals, and materials. Owing to the remoteness of the C5 and C6 positions, indoles of this family can be difficult to prepare, and often require multistep syntheses. Herein, we describe a concise process that converts simple derivatives of tyrosine into 5,6-difunctionalized indoles by direct oxidation of C?H, N?H, and O?H bonds. Our work draws inspiration from the biosynthetic polymerization of tyrosine to make melanin pigments, but makes an important departure to provide well-defined indole heterocycles.

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