4305-32-2 Usage
Chemical class
1H-Indole-2-carboxylic acid, 5-hydroxy-6-methoxy-, methyl ester belongs to the indole class of chemical compounds.
Natural occurrence
1H-Indole-2-carboxylic acid, 5-hydroxy-6-methoxy-, methyl ester is commonly found in various natural sources such as plants and fungi.
Pharmaceutical applications
It has been studied for its potential pharmaceutical applications, particularly in the field of medicinal chemistry and drug development.
Bioactive properties
The unique structural properties of 1H-Indole-2-carboxylic acid, 5-hydroxy-6-methoxy-, methyl ester make it a promising candidate for the synthesis of novel bioactive compounds with various biological activities, including antioxidant, anti-inflammatory, and anticancer properties.
Lipophilic properties
The methyl ester form of 1H-Indole-2-carboxylic acid, 5-hydroxy-6-methoxy-, methyl ester enhances its lipophilic properties, which can improve its bioavailability and pharmacokinetic profile in drug formulations.
Research and development potential
1H-Indole-2-carboxylic acid, 5-hydroxy-6-methoxy-, methyl ester holds potential for further research and development in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 4305-32-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,0 and 5 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 4305-32:
(6*4)+(5*3)+(4*0)+(3*5)+(2*3)+(1*2)=62
62 % 10 = 2
So 4305-32-2 is a valid CAS Registry Number.
4305-32-2Relevant academic research and scientific papers
A Bioinspired Synthesis of Polyfunctional Indoles
Huang, Zheng,Kwon, Ohhyeon,Huang, Haiyan,Fadli, Aziz,Marat, Xavier,Moreau, Magali,Lumb, Jean-Philip
supporting information, p. 11963 - 11967 (2018/09/11)
Polyfunctional indoles bearing substituents at C5 and C6 are prevalent in natural products, pharmaceuticals, agrochemicals, and materials. Owing to the remoteness of the C5 and C6 positions, indoles of this family can be difficult to prepare, and often require multistep syntheses. Herein, we describe a concise process that converts simple derivatives of tyrosine into 5,6-difunctionalized indoles by direct oxidation of C?H, N?H, and O?H bonds. Our work draws inspiration from the biosynthetic polymerization of tyrosine to make melanin pigments, but makes an important departure to provide well-defined indole heterocycles.