43057-77-8

Basic information

• Product Name: 4-ETHOXY-2-HYDROXY-BENZALDEHYDE
• Synonyms: 4-Ethoxysalicylaldehyde;Benzaldehyde,4-Ethoxy-2-Hydroxy
• CAS NO: 43057-77-8
• Molecular Formula: C₉H₁₀O₃
• Molecular Weight: 166.17
• Mol File: 43057-77-8.mol
• Article Data: 13

Chemical Properties

• Melting Point: 34 °C
• Boiling Point: 285 °C at 760 mmHg
• Flash Point: 114.1 °C
• Appearance: /
• Density: 1.186 g/cm³
• Vapor Pressure: 0.00167mmHg at 25°C
• Refractive Index: 1.573
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 7.84±0.10(Predicted)
• CAS DataBase Reference: 4-ETHOXY-2-HYDROXY-BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ETHOXY-2-HYDROXY-BENZALDEHYDE(43057-77-8)
• EPA Substance Registry System: 4-ETHOXY-2-HYDROXY-BENZALDEHYDE(43057-77-8)

Safety Data

• Hazardous Substances Data: 43057-77-8(Hazardous Substances Data)

Usage

General Description

4-Ethoxy-2-Hydroxy-Benzaldehyde is a chemical compound that is primarily utilized in the fields of pharmaceuticals and organic synthesis, often serving as an intermediate in the synthesis of certain chemicals. Its systematic name is 4-Ethoxy-2-hydroxybenzaldehyde, and it falls under the category of aromatic aldehydes. It chiefly contains elements such as carbon, hydrogen, and oxygen, with a molecular formula of C9H10O3. Its chemical structure is identified by the presence of an aldehyde group (-CHO), an ethoxy group (-C2H5O), and a hydroxy group (-OH) attached to a benzene ring. The compound appears as a solid powder or a crystalline substance under standard conditions.

InChI:InChI=1/C9H10O3/c1-2-12-8-4-3-7(6-10)9(11)5-8/h3-6,11H,2H2,1H3

Upstream product

• 74-96-4 ethyl bromide 
• 95-01-2 2,4-Dihydroxybenzaldehyde 
• 10031-82-0 4-ethoxybenzaldehyde 
• 75-03-6 ethyl iodide 

Downstream Products

• 42243-38-9 5-Ethoxy-2-{[(E)-4-pentyl-phenylimino]-methyl}-phenol 
• 93764-44-4 2-{[(E)-4-Butoxy-phenylimino]-methyl}-5-ethoxy-phenol 
• 42243-39-0 5-Ethoxy-2-{[(E)-4-hexyl-phenylimino]-methyl}-phenol 
• 42243-36-7 5-Ethoxy-2-{[(E)-4-propyl-phenylimino]-methyl}-phenol 
• 97586-31-7 5-Ethoxy-2-{[(E)-4-propoxy-phenylimino]-methyl}-phenol 
• 97586-30-6 5-Ethoxy-2-{[(E)-4-nonyl-phenylimino]-methyl}-phenol 
• 93739-40-3 4-ethoxy-2-hydroxybenzal-4'-amyloxyaniline 
• 93739-42-5 5-Ethoxy-2-{[(E)-4-octyloxy-phenylimino]-methyl}-phenol 
• 78545-00-3 5-Ethoxy-2-{[(E)-4-heptyl-phenylimino]-methyl}-phenol 
• 93739-41-4 5-Ethoxy-2-{[(E)-4-hexyloxy-phenylimino]-methyl}-phenol 
• 97586-29-3 5-Ethoxy-2-{[(E)-4-octyl-phenylimino]-methyl}-phenol 
• 94495-18-8 5-Ethoxy-2-{[(E)-4-heptyloxy-phenylimino]-methyl}-phenol 
• 42243-35-6 5-Ethoxy-2-{[(E)-4-ethyl-phenylimino]-methyl}-phenol 
• 67073-93-2 6-ethoxy-2-nitro-benzofuran 

Relevant articles and documents

The influence of molecular flexibility on the mesogenic behavior of a new homologous series based on azo-azomethine: Synthesis, characterization, photoisomerization and DFT study

Through condensation of 2-hydroxy-4-n-alkoxybenzaldehyde (n = 2 to 8, 10, 12, 14, 16, 18) with (E)-4-((2,4-dimethylphenyl)diazenyl) benzene-1,3-diamine, new homologous series of rod shaped calamite liquid crystals based on azo-azomethine have been prepared. All synthesized compounds were characterized by FT-IR, 1H NMR, and 13C NMR spectroscopy. Use Differential Scanning Calorimeter (DSC) and Polarizing Optical Microscope (POM) to check the liquid crystal properties of all synthetic compounds. In the homologous series, all the compounds are mesogenic; some of them are in the nematic phase; some of them appear in the smectic A phase, and some appear in the nematic and smectic A phases. UV–vis pectroscopy was used to study the photoisomerization in chloroform. DFT (Density functional theory) level calculations and complete geometric optimization of all synthetic compounds are performed using B3LYP/6-31+G (d, p) basis sets.

Synthesis, characterization, and mesomorphic properties of some new Schiff base homologues series and their Cu(II) complexes

In present study, we have synthesized two homologous series of some new Schiff base of 4-n-alkoxy-2-hydroxy benzaldehyde (n = 2–8, 10, 12, 14, 16, 18) with 4-amino acetanilide and their corresponding Cu(II) complexes. A series of new Schiff base containing two aromatic rings have been synthesized and characterized by various spectroanalytical techniques including FT-IR and 1H NMR. The mesomorphic properties of these compounds were observed by optical polarized light microscopy (POM) and confirmed by differential scanning calorimetry (DSC) study. It has been observed that all the newly synthesized compounds exhibit wide range SmA phase.

Schiff base of 4-n-alkoxy-2-hydroxy benzaldehyde with 4-amino acetophenone and their Cu(II) complexes: synthesis, characterization and mesomorphic behavior

New homologous series of Schiff’s base of 4-n-Alkoxy-2-hydroxy benzaldehyde (n = 2 to 8, 10, 12, 14, 16, 18) with 4-amino acetophenone and their Cu(II) metal complexes have been synthesized. The compounds were characterized using various spectroscopic techniques including FT-IR, 1H-NMR, 13C-NMR. Mesomorphic properties of these compounds have been investigated with polarizing optical microscope and differential scanning calorimeter. These compounds exhibit wide range SmA phase as confirmed by their typical optical texture under polarizing microscope.