43071-26-7

Upstream product

• 51414-50-7 methyl (2-methoxycarbonyl-3-oxo-1-cyclohexene)acetate 
• 74590-73-1 1,3-bis(trimethylsiloxy)-1-methoxybuta-1,3-diene 
• 149-73-5 trimethyl orthoformate 
• 1712-36-3 penta-2,3-dienedioic acid dimethyl ester 
• 110362-30-6 1-<(trimethylsilyl)oxy>-1-methoxy-1,3-butadiene 
• 42421-12-5 (2-carboxy-3-hydroxyphenyl)acetic acid 
• 496-64-0 3-hydroxy-2-pyrone 

Downstream Products

• 1214-87-5 methyl (2-carbomethoxy-3-methoxyphenyl)acetate 
• 42421-12-5 (2-carboxy-3-hydroxyphenyl)acetic acid 
• 477351-19-2 2-methoxycarbonylmethyl-6-trifluoromethanesulfonyloxy-benzoic acid methyl ester 
• 88036-13-9 C₂₃H₂₁ClO₈ 
• 74794-52-8 8-methoxyhomophthalic anhydride 
• 1137-31-1 2-carboxy-3-methoxybenzene-1-acetic acid 

Relevant academic research and scientific papers

Synthesis of the C1-C15 fragment of apicularen A through a regioselective electron-transfer-initiated cyclization reaction

In this paper we report the preparation of the benzyltetrahydropyran fragment of the vacuolar ATPase inhibitor apicularen A through an oxidative cyclization protocol. In this reaction regioselective cleavage of one homobenzylic ether in the presence of another homobenzylic ether is achieved by selectively weakening one carbon-carbon σ-bond through substitution. This work demonstrates that oxidative fragmentation reactions can be used to generate stable cations selectively, even in the presence of other readily oxidized groups, provided that bond cleavage is sufficiently rapid following oxidation. Georg Thieme Verlag Stuttgart.

Thiolalkyl benzoic acid derivatives

The present invention relates to new thiolalkyl benzoic acids, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase leve

Synthesis of homophthalates from allenic diesters: Conversion into viocristin and analogues, and application to 6-methylpretetramid

Oxy-substituted homophthalic anhydrides have been synthesized by cycloaddition of di- and tri-oxy butadienes to the allenic diester (1). By base-catalysed cycloaddition to appropriate benzoquinones they have afforded new syntheses of viocristin (19), isov

Synthesis of 8-Methoxy- and 8-Methoxy-6-methylhomophthalic Anhydrides, Key Intermediates for the Synthesis of Anthracyclinones and peri-Hydroxylated Polycyclic Aromatic Compounds

A novel synthesis of 8-methoxy- (1a) and 8-methoxy-6-methylhomophthalic anhydrides (1b) is described.Oxidative aromatization of methyl-2-(2-carbomethoxy-3-oxocyclohex-1-enyl)acetate (2) using 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) or sublimed sul

Chemistry of enol silyl ethers. A general synthesis of 3-hydroxyhomophthalates and a biomimetic synthesis of sclerin

A general synthesis of 3- hydroxyhomophthalates is developed and applied to the synthesis of sclerin (24), a compound possessing plant-growth activity; the critical step in the synthesis of 24 can be considered as the controlled condensation of a di-β-carbonyl unit with a tri-β-carbonyl unit.

Biomimetic Synthesis of Sclerin

A general synthesis of 3-hydroxy-homophthalates is developed and applied to the synthesis of sclerin (1), a compound possessing plant-growth activity; the critical step in the synthesis of (1) can be considered as the controlled condensation of a dicarbon