4309-23-3

Upstream product

• 99-94-5 p-Toluic acid 
• 17264-54-9 sodium p-methylbenzoate 
• 7758-99-8 copper(II) sulfate 
• 16518-25-5 potassium p-methyl benzoate 

Downstream Products

• 1579231-52-9 [copper(p-toluate)₂(2-(4-pyridyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide)₂] 
• 1459155-29-3 [Cu₂(4-MePhCOO)₄(2-(3-pyridyl)-4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazolyl-1-oxyl-3-oxide)₂] 
• 127837-69-8 [Cu(CH₃C₆H₄COO)((OCH₂)(HOCH₂)C₃H₄N₂S)]2 
• 168915-19-3 [Cu(CH₃C₆H₄COO)((OCH₂)(CH₃)C₃H₄N₂S)]2 
• 91730-66-4 [bis(4-methylbenzoate)quinoline N-oxide-copper(II)]2 

Relevant academic research and scientific papers

Synthesis, crystal structure, and DNA-binding properties of a new copper (II) complex containing mixed-ligands of 2,2′-bipyridine and p-methylbenzoate

A novel copper complex of [Cu(bpy)(pba)2·H 2O]·0.5H2O (bpy = 2,2′-bipyridine, pba = p-methylbenzoate) was synthesized. The interaction of the complex to native fish sperm DNA was investigated through electrochemistry, electronic absorption spectroscopy and viscosity experiments. In the X-ray crystallography structure, the copper (II) ion is coordinated by two oxygen atoms of two p-methylbenzoate groups, two nitrogen atoms of 2,2′-bipyridine and one water molecule. The observed changes in the physicochemical features of the copper (II) complex on binding to DNA suggested that the complex bind to DNA with intercalation mode via 2,2′-bipyridine ring into DNA base pairs. Electrochemical studies revealed that the complex prefer to bind to DNA in Cu(I) form rather than Cu(II) oxidation state form. Additionally, the nuclease activity of the title complex was assessed by gel electrophoresis assay and the results shown that the copper complex can cleave pBR322 DNA effectively in the presence of ascorbic acid.

Synthesis, magnetic and spectroscopic characterization of copper(II) toluate complexes with substituted piperazines

New copper(II) toluate complexes with the saturated heterocyclic bases [(L-L) having the tendency to coordinate through both 1 and 4 nitrogen atoms] 1-methylpiperazine, 1,4-dimethylpiperazine, 2,6-dimethylpiperazine and 1-phenylpiperazine have been prepared and characterized by physico-chemical and spectroscopic methods. All of the complexes were found to be antiferromagnetic with stoichiometries of the type Cu(OOCR)2(L-L)n (n = 1 or 0.5, R = 2-, 3-or 4-CH3C6H4) except Cu(OOCC6H4CH3-4)2(L-L) (where L-L = 2,6-dimethylpiperazine), which is magnetically dilute. The spin exchange parameter, -2J, for two of the antiferromagnetic complexes has been evaluated from magnetic susceptibility measurements at different temperatures. Binuclear copper(II) acetate monohydrate-like structure for the antiferromagnetic complexes of 1:1 stoichiometry and polymeric structure of the type Cu(OOCH) 2(dioxan)0.5 for the complexes of 1:0.5 stoichiometry have been proposed. The magnetically dilute complex has been assigned a polynuclear trans-pseudo-octahedral or polymeric square pyramidal structure. Copyright

Effects of Methyl Substituent on Solvent Extraction of Copper(II) with o-, m-, and p-Methylbenzoic Acids.

The extraction of copper(II) with o-, m-, and p-methylbenzoic acids in 1-octanol was carried out at 25 deg C and aqueous ionic strength of 0.1 mol dm-3 (NaClO4).In contrast to the extraction with benzoic acid, in which only the monomeric copper(II) benzoate is extracted, the dimeric copper(II) species is also responsible for the extraction of copper(II) with o- and m-methylbenzoic acids in 1-octanol together with the monomeric one.On the other hand, p-methylbenzoic acid has a poorer extracting capability than o- and m-methylbenzoic acids and only the monomeric copper(II) species is responsible for the extraction.