431075-59-1

Basic information

• Product Name: N-[(1-dimethylcarbamoyl)-2-phenylvinyl]benzamide
• Synonyms: N-[(1-dimethylcarbamoyl)-2-phenylvinyl]benzamide
• CAS NO: 431075-59-1
• Molecular Weight: 294.353
• Mol File: 431075-59-1.mol

Chemical Properties

• CAS DataBase Reference: N-[(1-dimethylcarbamoyl)-2-phenylvinyl]benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(1-dimethylcarbamoyl)-2-phenylvinyl]benzamide(431075-59-1)
• EPA Substance Registry System: N-[(1-dimethylcarbamoyl)-2-phenylvinyl]benzamide(431075-59-1)

Safety Data

• Hazardous Substances Data: 431075-59-1(Hazardous Substances Data)

Upstream product

• 124-40-3 dimethyl amine 
• 17606-70-1 (4Z)-4-benzylidene-2-phenyl-1,3-oxazol-5(4H)-one 
• 100-52-7 benzaldehyde 
• 842-74-0 4-benzylidene-2-phenyloxazole-5(4H)-one 
• 506-59-2 N,N-dimethylammonium chloride 
• 1608-26-0 Hexamethylphosphorous triamide 

Downstream Products

• 1643501-24-9 (Z)-N-(1-bromo-3-(dimethylamino)-3-oxo-1-phenylprop-1-en-2-yl)benzamide 
• 83657-74-3 N-benzoyl-DL-phenylalanine dimethylamide 

Relevant articles and documents

A concise approach to polysubstituted oxazoles from N-acyl-2-bromo enamides via a copper(i)/amino acid-catalyzed intramolecular C-O bond formation

A straightforward and efficient copper(i)/amino acid-catalyzed intramolecular Ullmann-type C-O coupling reaction has been developed. This protocol affords a facile methodology for the synthesis of a series of novel 2,4,5-substituted oxazoles from readily accessible N-acyl-2-bromo enamides under mild conditions. This journal is the Partner Organisations 2014.

Synthesis of new bisphosphonate and bisphosphonic acid derivatives and heterocyclic and dialkylcarbamoyl oxazolone derivatives with anticancer and antischistosomal activity

The reaction of 5(4H)-oxazolones with tetraethyl methanediylbis(phosphonate) afforded new 1,1-bisphosphonate and 1,1-bisphosphonic acid derivatives. Moreover, 5(4H)-oxazolones reacted with Wittig reagents to give the corresponding heterocyclic products. Treatment of 5(4H)-oxazolones with trisdialkylaminophosphanes gave the corresponding N-(1-dialkylcarbamoyl)-2-phenylvinylbenzamides. Mechanisms accounting for the formation of the new products are discussed. The biological activity of the newly synthesized compounds was also examined.