432552-79-9

Basic information

• Product Name: 4,1-Benzoxazepin-2(3H)-one, 5-(3-chlorophenyl)-7-[(4-chlorophenyl)hydroxy(1-methyl-1H-imidazol-5-yl )methyl]-1,5-dihydro-1-methyl-
• CAS NO: 432552-79-9
• Molecular Formula: C27H23Cl2N3O3
• Molecular Weight: 508.404
• Mol File: 432552-79-9.mol

Chemical Properties

• CAS DataBase Reference: 4,1-Benzoxazepin-2(3H)-one, 5-(3-chlorophenyl)-7-[(4-chlorophenyl)hydroxy(1-methyl-1H-imidazol-5-yl )methyl]-1,5-dihydro-1-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4,1-Benzoxazepin-2(3H)-one, 5-(3-chlorophenyl)-7-[(4-chlorophenyl)hydroxy(1-methyl-1H-imidazol-5-yl )methyl]-1,5-dihydro-1-methyl-(432552-79-9)
• EPA Substance Registry System: 4,1-Benzoxazepin-2(3H)-one, 5-(3-chlorophenyl)-7-[(4-chlorophenyl)hydroxy(1-methyl-1H-imidazol-5-yl )methyl]-1,5-dihydro-1-methyl-(432552-79-9)

Safety Data

• Hazardous Substances Data: 432552-79-9(Hazardous Substances Data)

Upstream product

• 190898-77-2 3-(3-chlorophenyl)-5-[2-(4-chlorophenyl)-1,3-dioxolan-2-yl]-2,1-benzisoxazole 
• 192187-38-5 (4-chlorophenyl)[3-(3-chlorophenyl)-2,1-benzisoxazol-5-yl]methanone 
• 432552-77-7 5-(3-chlorophenyl)-7-[(4-chlorophenyl)hydroxy(1-methyl-1H-imidazol-5-yl)methyl]-1,5-dihydro-4,1-benzoxazepin-2(3H)-one 
• 74-88-4 methyl iodide 
• 766-84-7 3-chloro-benzonitrile 
• 432553-06-5 2-bromo-N-[2-[(3-chlorophenyl)hydroxymethyl]4-[(4-chlorophenyl)hydroxy(1-methyl-1H-imidazol-5-yl)methyl]phenyl]-acetamide 
• 192187-40-9 (+/-)-[2-amino-5-[(4-chlorophenyl)hydroxy(1-methyl-1H-imidazol-5-yl)methyl]phenyl](3-chlorophenyl)methanone 
• 432553-05-4 4-amino-α3-(3-chlorophenyl)-α1-(4-chlorophenyl)-α1-(1-methyl-1H-imidazol-5-yl)-1,3-benzenedimethanol 
• 192187-39-6 (+/-)-3-(3-chlorophenyl)-α-(4-chlorophenyl)-α-(1-methyl-1H-imidazol-5-yl)-2,1-benzisoxazole-5-methanol 
• 190898-64-7 2-(4-Chlorophenyl)-2-(4-nitrophenyl)-1,3-dioxolane 
• 7497-60-1 (4-Chlorophenyl)(4-nitrophenyl)methanone 

Relevant articles and documents

Farnesyl transferase inhibiting benzoheterocyclic derivatives

This invention comprises the novel compounds of formula (I) wherein r, s, t, X, Z, R1, R2, R3, R4, R5, R6 and R7 have defined meanings, having farnesyl transferase inhibiting act

5-Imidazolyl-quinolinones, -quinazolinones and -benzo-azepinones as farnesyltransferase inhibitors

The evaluation of structure-activity relationships associated with the modification of the R115777 quinolinone ring moiety displaying potent in vitro inhibiting activity is described.