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2,4(1H,3H)-Pyrimidinedione, 1,3-dibenzoyl-5-methyl-, also known as 1,3-dibenzoyl-5-methyl-2,4(1H,3H)-pyrimidinedione, is a chemical compound with the molecular formula C19H15N2O3. It is a derivative of the pyrimidine ring system and is commonly used in pharmaceutical and organic synthesis as a key intermediate in the production of various drugs and active pharmaceutical ingredients. 2,4(1H,3H)-Pyrimidinedione, 1,3-dibenzoyl-5-methylhas a variety of applications in the pharmaceutical industry, where it is utilized in the synthesis of anticancer, anti-inflammatory, and antiviral drugs. Additionally, 1,3-dibenzoyl-5-methyl-2,4(1H,3H)-Pyrimidinedione has been found to exhibit potential antimicrobial and antioxidant activities, making it a versatile and important compound in the field of medicinal chemistry.

4330-16-9

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4330-16-9 Usage

Uses

Used in Pharmaceutical Industry:
2,4(1H,3H)-Pyrimidinedione, 1,3-dibenzoyl-5-methylis used as a key intermediate in the synthesis of various drugs and active pharmaceutical ingredients for its versatile chemical properties and potential therapeutic applications.
Used in Anticancer Drug Synthesis:
In the pharmaceutical industry, 1,3-dibenzoyl-5-methyl-2,4(1H,3H)-Pyrimidinedione is used as a precursor in the development of anticancer drugs, contributing to the creation of novel therapeutic agents that target cancer cells and inhibit their growth and proliferation.
Used in Anti-inflammatory Drug Synthesis:
2,4(1H,3H)-Pyrimidinedione, 1,3-dibenzoyl-5-methylis also utilized in the synthesis of anti-inflammatory drugs, where its unique structure and properties can be leveraged to develop medications that alleviate inflammation and associated symptoms.
Used in Antiviral Drug Synthesis:
1,3-dibenzoyl-5-methyl-2,4(1H,3H)-Pyrimidinedione is employed in the development of antiviral drugs, where its potential to inhibit viral replication and reduce the severity of viral infections makes it a valuable component in medicinal chemistry.
Used in Antimicrobial Applications:
Due to its potential antimicrobial activities, 2,4(1H,3H)-Pyrimidinedione, 1,3-dibenzoyl-5-methylis used in the development of antimicrobial agents, which can help combat bacterial infections and contribute to the treatment of various diseases.
Used in Antioxidant Applications:
The antioxidant properties of 1,3-dibenzoyl-5-methyl-2,4(1H,3H)-Pyrimidinedione make it a candidate for use in the development of antioxidant supplements or therapies, which can help protect cells from oxidative damage and promote overall health.

Check Digit Verification of cas no

The CAS Registry Mumber 4330-16-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,3 and 0 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4330-16:
(6*4)+(5*3)+(4*3)+(3*0)+(2*1)+(1*6)=59
59 % 10 = 9
So 4330-16-9 is a valid CAS Registry Number.

4330-16-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name N1,N3-dibenzoylthymine

1.2 Other means of identification

Product number -
Other names 1,3-dibenzoyl-5-methyl-1H-pyrimidine-2,4-dione

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:4330-16-9 SDS

4330-16-9Relevant academic research and scientific papers

CYCLOPENTYL NUCLEOSIDE ANALOGS AS ANTI-VIRALS

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Paragraph 0298, (2020/07/07)

Described herein are cyclopentyl nucleoside analogs, pharmaceutical compositions that include one or more cyclopentyl nucleoside analogs and methods of using the same to treat HBV, HDV and/or HIV.

Synthesis of nucleobase-functionalized β-peptoids and β-peptoid hybrids

Mejías, Xavier,Feliu, Lidia,Planas, Marta,Bardají, Eduard

, p. 8069 - 8071 (2007/10/03)

The solid-phase synthesis of a new class of nucleobase-modified peptide-mimetic oligomers is described. β-Peptoids and β-peptoid hybrids bearing thymine on the side chain are prepared from N-Fmoc-N-[2-(thymin-1-yl)ethyl]-β-alanine.

A short synthesis of 1-vinyluracil and 1-vinylthymine

Zhou, Jinglan,Shevlin, Philip B.

, p. 3591 - 3597 (2007/10/03)

1-Vinyluracil and 1-vinylthymine, monomers for nucleic acid bases attached functional polymers, were synthesized for the first time from uracil and thymine in 3 steps in 54% and 50% overall yields using the Mitsunobu reactions of 2a and 2b with 2-chloroet

THE BENZOYLATION OF URACIL AND THYMINE

Cruickshank, Kenneth A.,Jiricny, Josef,Reese, Colin B.

, p. 681 - 684 (2007/10/02)

Uracil and thymine react with benzoyl chloride in acetonitrile-pyridine solution at room temperature to give first their 1-N-benzoyl (2b and 3b) and then their 1-N,3-N-dibenzoyl derivatives (4a and 4b, respectively); the latter compounds are converted into the corresponding 3-N-benzoyl derivatives (5a and 6a) under mild conditions of basic hydrolysis.

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