4337-33-1Relevant articles and documents
Preparation method of (2-carboxyethyl) dimethyl sulfonium chloride
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Paragraph 0017-0019, (2021/01/11)
The invention belongs to the technical field of feed additives, and particularly relates to a preparation method of (2-carboxyethyl) dimethyl sulfonium chloride, which comprises the following steps: (1) dissolving 3-bromopropionic acid in an organic solvent under stirring conditions, adding sodium methyl mercaptide, carrying out heating reaction, adding water after the reaction finishes, regulating the pH value to 5-6 with hydrochloric acid, and extracting with ethyl acetate; washing an ethyl acetate layer with water after liquid separation, and carrying out rotary evaporation to remove ethylacetate and water to obtain an intermediate 3-(methylthio) propionic acid; and (2) under a stirring condition, adding the intermediate 3-(methylthio) propionic acid synthesized in the step (1) into ethyl acetate, cooling to below 2 DEG C in an ice bath, introducing chloromethane to react, carrying out suction filtration and drying after the reaction is finished to obtain a 2-(carboxyethyl) dimethyl sulfonium bromide crude product, and recrystallizing with absolute ethyl alcohol to obtain the target product (2-carboxyethyl) dimethyl sulfonium chloride. The method is environmentally friendly andeasier to operate, the yield of the synthesized (2-carboxyethyl) dimethyl sulfonium chloride is high, a foul smell pollution production process is abandoned, and the body health of production personnel is guaranteed.
Synthesis, structure, and antimicrobial activity of (carboxyalkyl)dimethylsulfonium halides
Bakhtiyarova, Yu. V.,Bakhtiyarov,Ivshin,Galkina,Krasnyuk,Gerasimov,Kataeva,Galkin
, p. 1903 - 1907 (2017/10/27)
Reactions of a series of ω-halocarboxylic acids (2-bromo-, 2-chloroethanoic, 3-bromo- and 3-chloropropanoic) with dimethyl sulfide resulted in the formation of stable (carboxylalkyl)dimethylsulfonium bromides and chlorides. Composition and structure of the salts obtained were established by a complex of chemical, physical and physicochemical methods. The sulfonium salts obtained showed high antibacterial and antimycotic activities with respect to the pathogenic microflora of humans and animals.
A dimethyl-β-propionic acid [...] method for the preparation of
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Paragraph 0008; 0023-0024, (2017/02/09)
The present invention relates to a preparation method for a novel attractant, and in particular relates to a preparation method for dimethyl-beta-sulfonioacetate. The present invention provides a new synthetic route which uses raw materials with wide and abundant sources and low prices. The product obtained according to the synthetic route has high purity, a good color and strong market competitiveness. The preparation method provided in the present invention sequentially comprises the following steps: adopting 3-hydroxypropionic acid as a raw material, protecting the hydroxyl group through reaction with methanesulfonyl chloride, and carrying out reaction with dimethylsulfide and acidification to prepare the dimethyl-beta-sulfonioacetate.