4341-02-0

Basic information

• Product Name: 2-(2-cyanophenyl)benzonitrile
• Synonyms: 2-(2-cyanophenyl)benzonitrile;[1,1'-Biphenyl]-2,2'-dicarbonitrile;1,1'-Biphenyl-2,2'-dicarbonitrile;2,2'-Dicyanobiphenyl
• CAS NO: 4341-02-0
• Molecular Formula: C₁₄H₈N₂
• Molecular Weight: 204.23
• Mol File: 4341-02-0.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 433.3°Cat760mmHg
• Flash Point: 218.1°C
• Appearance: /
• Density: 1.2g/cm³
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform (Slightly), DMSO (Slightly, Heated)
• CAS DataBase Reference: 2-(2-cyanophenyl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-cyanophenyl)benzonitrile(4341-02-0)
• EPA Substance Registry System: 2-(2-cyanophenyl)benzonitrile(4341-02-0)

Safety Data

• Hazardous Substances Data: 4341-02-0(Hazardous Substances Data)

Usage

General Description

2-(2-cyanophenyl)benzonitrile is a chemical compound with the molecular formula C14H8N2. It is a yellow crystalline powder that is commonly used as a building block in organic synthesis. 2-(2-cyanophenyl)benzonitrile is also known by the trade name DPA-3-CN, and is used in the production of liquid crystal materials, dyes, and pharmaceuticals. It is considered to be potentially hazardous, and exposure to 2-(2-cyanophenyl)benzonitrile may cause irritation to the skin, eyes, and respiratory tract. Therefore, proper safety precautions and handling procedures should be followed when working with this chemical.

Upstream product

• 873-32-5 2-Chlorobenzonitrile 
• 591-87-7 Allyl acetate 
• 2042-37-7 o-cyanobromobenzene 
• 2549-31-7 4-methyl-2,5-diphenyloxazole 
• 120914-99-0 3-phenyl-phenanthro<9,10-e>-1,2,4-triazine 
• 1003046-47-6 3-(p-chlorophenyl)phenanthro[9,10-e][1,2,4]triazine 
• 1003046-49-8 3-p-tolylphenanthro[9,10-e][1,2,4]triazine 
• 1126-46-1 Methyl 4-chlorobenzoate 
• 106-38-7 para-bromotoluene 
• 530-48-3 1,1-Diphenylethylene 
• 874-05-5 3-aminoindazole 
• 106-43-4 para-chlorotoluene 
• 5713-61-1 thiophen-2-yl magnesium bromide 
• 4890-63-5 (phenylethynyl)magnesium chloride 

Downstream Products

• 1329995-36-9 Ni[C₃₈H₁₄N₈(OC₆H₄C₄H₉)6] 
• 1289556-17-7 Ni[C₃₈H₁₄N₈(C₆H₄C₄H₉)6] 
• 84-11-7 9,10-phenanthrenequinone 
• 107011-08-5 bis{2,2'-bis(2-imidazolyl)biphenyl} 
• 126664-76-4 2,2'-bis(2-imidazolinyl)biphenyl 

Relevant articles and documents

Cu-Catalyzed Denitrogenative Transannulation of 3-Aminoindazoles to Assemble 1-Aminoisoquinolines and 3-Aminobenzothiophenes

We disclose a novel Cu-catalyzed denitrogenative transannulation of 3-aminoindazoles to afford diverse functionalized 3-aminobenzothiophenes and 1-aminoisoquinolines, in which denitrogenative transannulation of 3-aminoindazoles is reported for the first t

An efficient preparation for 2-Cyano-4'-methylbiphenyl in toluene-tetrahydrofuran solvents over transition-metal catalysts

2-Cyano-4'-methyl-biphenyl, which is a key intermediate used for the preparation of anti-hypertensive drugs, was easily synthesized by the coupling of non-active o-chlorobenzonitrile with p-chlorotoluene in toluene-tetrahydrofuran mixed solvents over transition-metal catalysts. Various reaction conditions, especially catalysis of some catalysts were discussed to improve selectivity suitable for industrialization in the recycle solvent system.

Efficient cobalt-catalyzed formation of unsymmetrical biaryl compounds and its application in the synthesis of a sartan intermediate

(Chemical Equation Presented) No prior preparation of the organometallic reagent is required in a cobalt-catalyzed coupling of two different aryl halides under mild conditions (see scheme). A broad spectrum of valuable biaryl compounds can be prepared in this way. Not only may a variety of reactive substituents be present, but heteroaryl halides and aryl triflates are also suitable substrates. DMF = N,N-dimethylformamide, FG = functional group.