437384-08-2Relevant academic research and scientific papers
Pyrazolopyridine antiherpetics: SAR of C2′ and C7 amine substituents
Johns, Brian A.,Gudmundsson, Kristjan S.,Turner, Elizabeth M.,Allen, Scott H.,Samano, Vicente A.,Ray, John A.,Freeman, George A.,Boyd Jr., F. Leslie,Sexton, Connie J.,Selleseth, Dean W.,Creech, Katrina L.,Moniri, Kelly R.
, p. 2397 - 2411 (2007/10/03)
A novel series of potent pyrazolo[1,5-a]pyridine inhibitors of herpes simplex virus 1 replication have been identified. Several complimentary synthetic methods were developed to allow facile access to a diverse set of analogs from common late stage interm
Therapeutic compounds
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, (2008/06/13)
The present invention provides compounds of formula (I): wherein all variables are as defined herein, pharmaceutical compositions containing the same, processes for preparing the same and their use as pharmaceutical agents. 1
Pyrazolo[1,5-a]pyridines: Synthetic approaches to a novel class of antiherpetics
Johns, Brian A.,Gudmundsson, Kristjan S.,Turner, Elizabeth M.,Allen, Scott H.,Jung, David K.,Sexton, Connie J.,Boyd Jr., F. Leslie,Peel, Michael R.
, p. 9001 - 9011 (2007/10/03)
Synthesis of a novel class of 7-amino-3-pyrimidinyl-pyrazolo[1,5-a] pyridine antiherpetic compounds is described. The synthetic methodology is designed to allow for rapid analog synthesis around the C-3 and C-7 positions of the pyrazolo[1,5-a]pyridine. Th
