4374-69-0

Basic information

• Product Name: 3-ethyl-3-phenylbenzofuran-2(3H)-one
• Synonyms: 3-ethyl-3-phenylbenzofuran-2(3H)-one
• CAS NO: 4374-69-0
• Molecular Weight: 238.286
• Mol File: 4374-69-0.mol

Chemical Properties

• CAS DataBase Reference: 3-ethyl-3-phenylbenzofuran-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ethyl-3-phenylbenzofuran-2(3H)-one(4374-69-0)
• EPA Substance Registry System: 3-ethyl-3-phenylbenzofuran-2(3H)-one(4374-69-0)

Safety Data

• Hazardous Substances Data: 4374-69-0(Hazardous Substances Data)

Upstream product

• 36724-24-0 3-ethylbenzo[b]furan 
• 591-50-4 iodobenzene 
• 75-03-6 ethyl iodide 

Relevant articles and documents

Palladium-catalyzed bisarylation of 3-alkylbenzofurans to 3-arylalkyl-2-arylbenzofurans on water: Tandem C(sp3)-H and C(sp2)-H activation reactions of 3-alkylbenzofurans

A protocol involving facile sequential C(sp3)-H and C(sp2)-H activation reactions of 3-alkylbenzofurans catalyzed by Pd(OAc)2 in the presence of pivalic acid, silver salt, and tricyclohexylphosphine 'on water' was developed. Aryl iodides were used as substrates in a tandem bisarylation reaction to generate 3-arylalkyl-2-arylbenzofurans in moderate to high yields at room temperature. The reaction revealed in this study is a rare example of consecutive C(sp3)-H and C(sp2)-H bond activation under mild reaction conditions.