36724-24-0

Basic information

• Product Name: Benzofuran, 3-ethyl-
• Synonyms: Benzofuran, 3-ethyl-
• CAS NO: 36724-24-0
• Molecular Formula: C₁₀H₁₀O
• Molecular Weight: 146.1858
• Mol File: 36724-24-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzofuran, 3-ethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzofuran, 3-ethyl-(36724-24-0)
• EPA Substance Registry System: Benzofuran, 3-ethyl-(36724-24-0)

Safety Data

• Hazardous Substances Data: 36724-24-0(Hazardous Substances Data)

Upstream product

• 7169-34-8 3-oxo-2,3-dihydrobenzo[b]furan 
• 925-90-6 ethylmagnesium bromide 
• 1745-81-9 o-Allylphenol 
• 19728-14-4 2-(2-propanoylphenoxy)acetic acid 
• 1188474-17-0 1-(but-2-yn-1-yloxy)-2-iodobenzene 
• 100612-85-9 ethyl 2-(2-propanoylphenoxy)acetate 
• 610-99-1 1-(2-Hydroxy-phenyl)-propan-1-on 
• 136229-41-9 1-(benzofuran-3-yl)ethyl bromide 
• 33494-47-2 2-(cyclopropylmethyl)-phenol 
• 127-09-3 sodium acetate 
• 746630-77-3 o-propionylphenoxyacetic acid 
• 26929-26-0 1-acetoxy-1-(benzo[b]furan-3-yl)ethane 
• 120568-90-3 (E)-1-(but-2-en-1-yloxy)-2-iodobenzene 

Downstream Products

• 15817-85-3 1-(3-ethyl-2-benzofuranyl)-ethanon 
• 4374-69-0 3-ethyl-3-phenylbenzofuran-2(3H)-one 

Relevant articles and documents

COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING CFTR

The present disclosure is directed to disclosed compounds that modulate, e.g., address underlying defects in cellular processing of CFTR activity.

Practical metal- and additive-free methods for radical-mediated reduction and cyclization reactions

Two facile, metal- and additive-free protocols for radical dehalogenation, deoxygenation and cyclization reactions are reported. Irradiation by household fluorescent light bulbs or the presence of an air atmosphere is shown to initiate the desired reactions, thus providing highly practical reaction setups for radical-mediated reductions and cyclizations.

Heterocyclization by catalytic carbonickelation of alkynes: A domino sequence involving vinylnickels

Reaction of Ni(0) in the presence of iodoarylethers 1 leads, after syn intramolecular carbonickelation of the triple bond, to nucleophilic vinylnickels which can be trapped, in a tandem process, by various electrophiles introduced at the onset of the reac

Preparation of 2-, 3-, 4- and 7-(2-alkylcarbamoyl-1-alkylvinyl)benzo[b] furans and their BLT1 and/or BLT2 inhibitory activities

Several 2-alkylcarbamoyl-1-alkylvinylbenzo[b]furans were designed to find a selective leukotriene B4 (LTB4) receptor antagonist. 2-(2-Alkylcarbamoyl-1-alkylvinyl)benzo[b]furans having a substituent group at the 3-position, 4-(2-alkylcarbamoyl-1-methylvinyl)benzo[b]furans having a substituent group at the 3-position, and 7-(2-alkylcarbamoyl-1-methylvinyl) benzo[b]furans and 3-(2-alkylcarbamoyl-1-alkylvinyl)benzo[b]furans were prepared and evaluated for LTB4 receptor (BLT1 and BLT 2) inhibitory activities. (E)-3-Amino-4-[2-[2-(3,4-dimethoxyphenyl) ethylcarbamoyl]-1-methylvinyl]benzo[b]furan ((E)-17c) showed potent and selective inhibitory activity for BLT2. On the other hand, (E)-7-(2-diethylcarbamoyl-1-methylvinyl)benzo[b]furan ((E)-27a) showed potent inhibitory activity for both BLT1 and BLT2. This journal is The Royal Society of Chemistry.

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Palladium-catalyzed oxidative activation of arylcyclopropanes

(Diagram presented) Palladium chloride-catalyzed intramolecular activation of electroneutral cyclopropane derivatives results in cleavage of the cyclopropane ring followed by formation of heterocyclic derivatives. Phenols, carboxylic acids, and amide groups were considered as substituents ortho to the cyclopropane ring in this catalytic activation chemistry. The regioselectivity observed in the case of amide-containing substrates was different from that of carboxylic acid-containing substrates, ruling out simple cyclopropane isomerization followed by a Wacker oxidation as the mechanistic pathway.

Vinylindenes and Some Heteroanalogues in the Diels-Alder Reaction. IX. 3-Vinylbenzofuran and 1,4-Naphthoquinone

3-Vinylbenzofuran and 1,4-naphthoquinone react to give r-5a,6,c-12a,c,12b-tetrahydroanthrabenzofuran-5,13-quinone.This adduct undergoes ring opening to 2-(2-hydroxyphenyl)anthraquinone with base and oxygen, but shows no rearrangement to anthrabenzofuran-5,13-quinone.

SYNTHESIS OF BENZOFURANS VIA PALLADIUM-PROMOTED CYCLIZATION OF ORTHO-SUBSTITUTED ARYL ALLYL ETHERS

o-Iodo- or (chloromercurio)aryl allyl ethers undergo facile palladium-promoted cyclization to benzofurans.