4383-30-6

Basic information

• Product Name: 9,11-Epoxypregn-4-ene-17,21-diol-3,20-dione 21-acetate
• Synonyms: 9,11-Epoxy-17,21-dihydroxypregn-4-one-3,20-dione 21-acetate;9,11-Epoxypregn-4-ene-17,21-diol-3,20-dione 21-acetate
• CAS NO: 4383-30-6
• Molecular Formula: C₂₃H₃₀O₆
• Molecular Weight: 402.48
• Mol File: 4383-30-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 569.2°Cat760mmHg
• Flash Point: 195.5°C
• Appearance: /
• Density: 1.3g/cm³
• Vapor Pressure: 2.51E-15mmHg at 25°C
• Refractive Index: 1.583
• CAS DataBase Reference: 9,11-Epoxypregn-4-ene-17,21-diol-3,20-dione 21-acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 9,11-Epoxypregn-4-ene-17,21-diol-3,20-dione 21-acetate(4383-30-6)
• EPA Substance Registry System: 9,11-Epoxypregn-4-ene-17,21-diol-3,20-dione 21-acetate(4383-30-6)

Safety Data

• Hazardous Substances Data: 4383-30-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C23H30O6/c1-13(24)28-12-18(26)22(27)9-7-16-17-5-4-14-10-15(25)6-8-20(14,2)23(17)19(29-23)11-21(16,22)3/h10,16-17,19,27H,4-9,11-12H2,1-3H3

Upstream product

• 50733-54-5 21-acetoxy-9-bromo-11β,17-dihydroxy-pregn-4-ene-3,20-dione 
• 113862-93-4 21-acetoxy-17-hydroxy-11α-methanesulfonyloxy-pregn-4-ene-3,20-dione 
• 566-35-8 Epicortisol 
• 7753-60-8 anecortave 
• 112248-25-6 9,21-dibromo-11β,17-dihydroxy-pregn-4-ene-3,20-dione 

Downstream Products

• 514-36-3 fludrocortisone acetate 
• 29042-01-1 21-acetoxy-9-chloro-11β,17-dihydroxy-pregn-4-ene-3,20-dione 
• 6635-85-4 21-acetoxy-11β,17-dihydroxy-9-methoxy-pregn-4-ene-3,20-dione 
• 10072-97-6 9,11β-epoxy-17,21-dihydroxy-9β-pregn-4-ene-3,20-dione 
• 96843-89-9 21-acetoxy-11β,17-dihydroxy-pregna-4,8(14)-diene-3,20-dione 
• 127-31-1 Fludrocortisone 
• 357-09-5 9α-Fluor-11β-hydroxy-3,17-dioxo-androsten-4 
• 79-60-7 9α-fluorocortisone 

Relevant articles and documents

Acyclic amine epoxide process

Acyclic amines are used to transform 9α-substituted-11β-hydroxy 21-acyloxy steroids to the corresponding 9β,11β-epoxy 21-acyloxy steroids without removal of the C17 or C21 ester. The acyclic amines are cheaper and easier to prepare than previously disclosed dehydrohalogenating agents which do not produce cleavage of the C21 ester.