440679-63-0Relevant academic research and scientific papers
β-Lactams in synthesis: short syntheses of cobactin analogs
Walz, Andrew J.,Miller, Marvin J.
, p. 5103 - 5105 (2008/02/09)
Mycobactins facilitate assimilation of iron by mycobacteria. Synthetic analogs with structural variation of the cobactin component have potent anti-TB activity. A new method for the synthesis of cobactin analogs is presented. The key process involves sing
Synthesis and studies of catechol-containing mycobactin S and T analogs
Walz, Andrew J.,Moellmann, Ute,Miller, Marvin J.
, p. 1621 - 1628 (2008/02/07)
The syntheses of catechol-containing mycobactin S and T analogs are described. These analogs incorporate a catechol-glycine moiety in place of the phenol-oxazoline of the naturally occurring mycobactins S and T. Studies indicated that the new siderophore
Synthesis and Biological Activity of Hydroxamic Acid-Derived Vasopeptidase Inhibitor Analogues
Walz, Andrew J.,Miller, Marvin J.
, p. 2047 - 2050 (2007/10/03)
(Equation Presented) Syntheses of novel hydroxamic acid-derived azepinones containing pendant mercaptoacyl groups or formyl hydroxamates are described. These new analogues of therapeutically important ACE and NEP inhibitors include unprecedented changes a
