210547-90-3

Upstream product

• 440679-63-0 C₆H₁₄N₂O₂C₈H₆O₂C₇H₄O 
• 440679-64-1 ((S)-1-Hydroxy-2-oxo-azepan-3-yl)-carbamic acid benzyl ester 
• 171287-52-8 C₂₁H₃₂N₂O₅ 
• 171287-55-1 (S)-2-Benzyloxycarbonylamino-6-hydroxyamino-hexanoic acid tert-butyl ester 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 112157-39-8 Nα-(Benzyloxycarbonyl)-L-lysine tert-butyl ester 
• 2212-75-1 N₂-[(benzyloxy)carbonyl]-L-lysine 

Downstream Products

• 171287-63-1 (R)-N-[(S)-1-(tert-Butyl-diphenyl-silanyloxy)-2-oxo-azepan-3-yl]-3-hydroxy-butyramide 
• 210547-96-9 {2-[(S)-1-(tert-Butyl-diphenyl-silanyloxy)-2-oxo-azepan-3-ylcarbamoyl]-ethyl}-carbamic acid benzyl ester 
• 210547-98-1 {(S)-2-Benzyloxyamino-1-[(S)-1-(tert-butyl-diphenyl-silanyloxy)-2-oxo-azepan-3-ylcarbamoyl]-ethyl}-carbamic acid tert-butyl ester 
• 284470-00-4 (S)-3-Hydroxy-2,2-dimethyl-decanoic acid [(S)-1-(tert-butyl-diphenyl-silanyloxy)-2-oxo-azepan-3-yl]-amide 
• 370103-06-3 (S)-2-(2-Hydroxy-phenyl)-4,5-dihydro-oxazole-4-carboxylic acid [(S)-1-{2-[(S)-1-(tert-butyl-diphenyl-silanyloxy)-2-oxo-azepan-3-ylcarbamoyl]-ethylcarbamoyl}-5-(hexadecanoyl-hydroxy-amino)-pentyl]-amide 
• 284470-02-6 6-[formyl-(2-trimethylsilanyl-ethoxymethoxy)-amino]-2-{[2-(2-hydroxy-5-methoxy-phenyl)-5-methyl-oxazole-4-carbonyl]-amino}-hexanoic acid 1-{1-[1-(tert-butyl-diphenyl-silanyloxy)-2-oxo-azepan-3-ylcarbamoyl]-1-methyl-ethyl}-octyl ester 
• 284470-01-5 (R)-2-Benzyloxycarbonylamino-6-[formyl-(2-trimethylsilanyl-ethoxymethoxy)-amino]-hexanoic acid (S)-1-{1-[(S)-1-(tert-butyl-diphenyl-silanyloxy)-2-oxo-azepan-3-ylcarbamoyl]-1-methyl-ethyl}-octyl ester 
• 1027428-89-2 (R)-2-Amino-6-[formyl-(2-trimethylsilanyl-ethoxymethoxy)-amino]-hexanoic acid (S)-1-{1-[(S)-1-(tert-butyl-diphenyl-silanyloxy)-2-oxo-azepan-3-ylcarbamoyl]-1-methyl-ethyl}-octyl ester 
• 225505-59-9 amamistatin A 

Relevant academic research and scientific papers

Total Synthesis of the Proposed Structure of Mycobactin J

The total synthesis of the proposed structure of mycobactin J (MJ), a metabolite of Mycobacterium tuberculosis, is presented. The highlights of the synthesis include a careful control of the Z-stereochemistry of the unsaturated long chain fatty acid, a biomimetic construction of the oxazoline building block and the carriage of an unprotected phenol throughout the synthesis.

Total synthesis of a mycobactin S, a siderophore and growth promoter of Mycobacterium Smegmatis, and determination of its growth inhibitory activity against Mycobacterium tuberculosis

A general total synthesis of mycobactins, represented by a mycobactin S, was achieved by a convergent approach. Two hydroxamic acid residues, 28 and 40b, were prepared from commercially available N(α)-Cbz-L-lysine via dimethyldioxirane oxidations. Cycliza