441016-68-8Relevant academic research and scientific papers
General Routes to 4-Methyl-2-substituted-furans: a Total Synthesis of Pleraplysillin-2, a Metabolite of the Sponge, Pleraplysilla spinifera
Knight, David W.,Rustidge, David C.
, p. 679 - 683 (1981)
A general approach to 4-methyl-2-substituted-furans is described in which 4-methyl-2-furyl-lithium is the key intermediate.Using this method, pleraplysillin-2, a sesquiterpenoid ester from the sponge Pleraplysilla spinifera, has been synthesised.An alternative, less efficient, route to this type of furan, via acyclic keto-epoxides, is also discussed.
