441072-21-5

Basic information

• Product Name: 2-(2-(trifluoromethyl)phenyl)pyridine
• Synonyms: 2-(2-(trifluoromethyl)phenyl)pyridine
• CAS NO: 441072-21-5
• Molecular Weight: 223.197
• Mol File: 441072-21-5.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 2-(2-(trifluoromethyl)phenyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-(trifluoromethyl)phenyl)pyridine(441072-21-5)
• EPA Substance Registry System: 2-(2-(trifluoromethyl)phenyl)pyridine(441072-21-5)

Safety Data

• Hazardous Substances Data: 441072-21-5(Hazardous Substances Data)

Upstream product

• 109-04-6 2-bromo-pyridine 
• 1073339-21-5 4,4,5,5-tetramethyl-2-(2-(trifluoromethyl)phenyl)-1,3,2-dioxaborolane 
• 628-13-7 pyridine hydrochloride 
• 88-17-5 2-(trifluoromethyl)benzenamine 
• 395-47-1 [2-(trifluoromethyl)phenyl]magnesium bromide 
• 1008-89-5 2-phenylpyridine 
• 129946-88-9 Umemoto's reagent 
• 887144-97-0 Togni's reagent 
• 1423-27-4 2-(trifluoromethyl)phenylboronic acid 
• 109-09-1 2-chloropyridine 
• 88-16-4 1-chloro-2-(trifluoromethyl)benzene 

Downstream Products

• 1236046-61-9 C₁₉H₁₂F₃NO 
• 1609120-85-5 2-{2-phenylthio-6-(trifluoromethyl)phenyl}pyridine 
• 1251668-01-5 2-[4'-methoxy-3-(trifluoromethyl)-[1,1'-biphenyl]-2-yl]pyridine 
• 1394856-82-6 2-[2-iodo-6-(trifluoromethyl)phenyl]pyridine 

Relevant articles and documents

Green-emitting iridium(iii) complexes containing pyridine sulfonic acid as ancillary ligands for efficient OLEDs with extremely low efficiency roll-off

A novel ancillary ligand of pyridine sulfonic acid (PySO3) was developed for two green-emitting iridium(iii) compounds, Ir1 (λmax = 496 nm) and Ir2 (λmax = 504 nm), with trifluoromethyl-substituted 2-phenylpyridine derivatives as the main ligands. Due to the strong electron-withdrawing ability of PySO3, both complexes have relatively low LUMO energy levels and good electron mobility, which benefit the charge balance in the organic light-emitting diodes (OLEDs) during the electroluminescence process. Therefore, all devices with double light-emitting layers exhibit good performances. In particular, the device using Ir2 as an emitter obtains a maximum luminance above 92000 cd m-2, a maximum external quantum efficiency (EQEmax) of 25.5% with an extremely low efficiency roll-off, and the EQE still remains at 22.9% at the high luminance of 20000 cd m-2. These results demonstrate that pyridine sulfonic acid is a potential and charming ligand for Ir(iii) complexes and high-performance OLEDs.

Copper-catalyzed cross-coupling of aryl-, primary alkyl-, and secondary alkylboranes with heteroaryl bromides

A method for the Cu-catalyzed cross-coupling of both aryl and alkylboranes with aryl bromides is described. The method employs an inexpensive Cu-catalyst and functions for a variety of heterocyclic as well as electron deficient aryl bromides. In addition, aryl iodides of varying substitution patterns and electronic properties work well.

Direct Alkenylation of Allylbenzenes via Chelation-Assisted C-C Bond Cleavage

A novel method for direct transformation of allyl groups in allylbenzene derivatives to alkenyl groups via rhodium-catalyzed C-C bond cleavage is reported. The alkenylation with styrenes of allylbenzenes containing pyridyl and pyrazolyl groups as a directing group proceeded efficiently to give alkenylation products. We also developed a new protocol for transformation of an ortho-prenylated phenol to an aniline derivative.