4419-94-7

Basic information

• Product Name: P-NITROPHENYL BETA-D-LACTOPYRANOSIDE
• Synonyms: GAL1-B-4GLC1-B-PNP;4-NITROPHENYL-BETA-D-LACTOPYRANOSIDE;4-NITROPHENYL-BETA-D-LACTOSIDE;P-NITROPHENYL BETA-D-LACTOPYRANOSIDE;P-NITROPHENYL-BETA-D-LACTOSIDE;PNP-BETA-D-LAC;4-nitrophenyl β-d-lactopyranoside;4-Nitrophenylb-D-lactopyranoside
• CAS NO: 4419-94-7
• Molecular Formula: C₁₈H₂₅NO₁₃
• Molecular Weight: 463.39
• EINECS: 1533716-785-6
• Product Categories: Oligosaccharides;Lactoside;Activity;Chromogenic;ChromogenicSubstrates;Enzyme Substrates;substrate
• Mol File: 4419-94-7.mol
• Article Data: 22

Chemical Properties

• Melting Point: 263-265°C
• Boiling Point: 795.6±60.0 °C(Predicted)
• Appearance: white/powder
• Density: 1.70±0.1 g/cm3 (20 oC 760 Torr), Calc.*
• Refractive Index: 1.671
• Storage Temp.: −20°C
• Solubility: Water (Slightly, Heated)
• PKA: 12.43±0.70(Predicted)
• CAS DataBase Reference: P-NITROPHENYL BETA-D-LACTOPYRANOSIDE(CAS DataBase Reference)
• NIST Chemistry Reference: P-NITROPHENYL BETA-D-LACTOPYRANOSIDE(4419-94-7)
• EPA Substance Registry System: P-NITROPHENYL BETA-D-LACTOPYRANOSIDE(4419-94-7)

Safety Data

• Hazard Codes: T
• Statements: 61
• Safety Statements: 53-45
• WGK Germany: 3
• Hazardous Substances Data: 4419-94-7(Hazardous Substances Data)

Usage

Chemical Properties

White Crystalline Solid

Uses

Different sources of media describe the Uses of 4419-94-7 differently. You can refer to the following data:
1. p-Nitrophenyl β-D-Lactopyranoside is a useful compound
2. 4-Nitrophenyl β-D-lactopyranoside may be used as a substrate for determining β-lactosidase activity and for determining the substrate specificity for β-glucosidase from the yeast Debaryomyces hansenii. It has also been used as a substrate for cellobiohydrolase.

InChI:InChI=1/C18H25NO13/c20-5-9-11(22)12(23)14(25)18(30-9)32-16-10(6-21)31-17(15(26)13(16)24)29-8-3-1-7(2-4-8)19(27)28/h1-4,9-18,20-26H,5-6H2/t9?,10?,11-,12-,13+,14-,15-,16+,17+,18-/m0/s1

Upstream product

• 84034-75-3 4-nitrophenyl-2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-(1→4)-2,3,6-tetra-O-acetyl-β-D-glucopyranoside 
• 2492-87-7 4-nitrophenyl-β-D-glucoside 
• 2021-84-3 α-galactosyl fluoride 
• 133-89-1 uridine-5'-diphosphogalactose 
• 439-03-2 2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl fluoride 
• 25878-60-8 D-galactose pentaacetate 
• 5987-78-0 p-nitrophenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyde 
• 100-02-7 4-nitro-phenol 
• 604-69-3 β-D-glucose pentaacetate 
• 31363-98-1 (4-nitro-phenyl)-[O²,O³,O⁶-triacetyl-O⁴-(tetra-O-acetyl-α-D-glucopyranosyl)-α-D-glucopyranoside] 
• 7585-39-9 β‐cyclodextrin 
• 3767-28-0 4-nitrophenyl-α-D-glucopyranoside 
• 69-79-4 D-maltose 
• 66068-37-9 4-nitrophenyl α-maltotetraoside 

Downstream Products

• 42935-29-5 (4-amino-phenyl)-(O⁴-α-D-glucopyranosyl-β-D-glucopyranoside) 
• 100-02-7 4-nitro-phenol 
• 3767-28-0 4-nitrophenyl-α-D-glucopyranoside 
• 1402245-83-3 C₂₄H₃₅NO₁₈ 
• 1402245-94-6 C₄₄H₅₅NO₂₈ 
• 2149582-14-7 4-nitrophenyl O-(5-acetamido-3,5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosylonicacid)-(2→3)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranoside 
• 94367-66-5 p-succinylamidophenyl β-lactoside 
• 492-62-6 alpha-D-glucopyranose 
• 2149582-14-7 α-D-Neu5Ac-(2->3)-β-D-Gal-(1->4)-β-D-Glc-OC6H4NO2-p 
• 148705-00-4 p-nitrophenyl 3',4'-O-isopropylidene-β-lactoside 
• 17691-02-0 p-Aminophenyl 4-O-(β-D-galactopyranosyl)-β-D-glucopyranoside 

Relevant articles and documents

SYNTHETIC CATALYSTS FOR CARBOHYDRATE PROCESSING

The disclosure relates to molecularly-imprinted cross-linked micelles that can selectively hydrolyze carbohydrates.

BEVERAGE DISPENSING EQUIPMENT

Apparatus and methods for reducing biofouling in drink such as beer dispensing equipment are described.

Environmentally benign glycosylation of aryl pyranosides and aryl/alkyl furanosides demonstrating the versatility of thermostable CGTase from Thermoanaerobacterium sp.

An extensive study on the specificity of transglycosylation and disproportionation of Thermoanaerobacterium sp. cyclodextrin glucosyltransferases against aryl glucopyranosides or furanosides is reported. While a mixture of maltoside and isomaltoside was obtained respectively using p-nitrophenyl glucopyranoside as an acceptor, only one regioisomer, namely p-nitrophenyl α-d-Glcp-(1,3)-α-l-Araf, was isolated using p-nitrophenyl arabinofuranoside as an acceptor. Interestingly, similar outcomes were found when using p-nitrophenyl galactofuranoside. Furthermore, activation by microwave irradiation resulted in faster reaction times and higher yields and led to glucosidic oligosaccharides with up to 70% conversion. The influence of the anomeric and C-4 configurations of the glycosidic acceptors on the transglycosylation, previously stated for the CGTase family, was not observed and unconventional substrate specificity towards alkyl furanosides was highlighted. This journal is the Partner Organisations 2014.