444002-56-6

Basic information

• Product Name: 4-(4-amino-phenyl)-3-oxopiperazine-1-carboxylic acid tert-butyl ester
• Synonyms: 4-(4-amino-phenyl)-3-oxopiperazine-1-carboxylic acid tert-butyl ester
• CAS NO: 444002-56-6
• Molecular Weight: 291.35
• Mol File: 444002-56-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 4-(4-amino-phenyl)-3-oxopiperazine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-amino-phenyl)-3-oxopiperazine-1-carboxylic acid tert-butyl ester(444002-56-6)
• EPA Substance Registry System: 4-(4-amino-phenyl)-3-oxopiperazine-1-carboxylic acid tert-butyl ester(444002-56-6)

Safety Data

• Hazardous Substances Data: 444002-56-6(Hazardous Substances Data)

Upstream product

• 1022128-82-0 C₁₀H₁₃N₃O 
• 24424-99-5 di-tert-butyl dicarbonate 
• 76003-29-7 4-(t-butyloxycarbonyl)piperazin-2-one 
• 106-40-1 4-bromo-aniline 
• 540-37-4 p-aminoiodobenzene 

Relevant articles and documents

PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER

The invention provides compounds of the formula (1): or a salt or tautomer thereof wherein A, R1, R2, R3, R4, R5 and R6 are as defined herein. The compounds are inhibitors of Wee1 and/or PLK1 kinase and are envisaged to be useful in the treatment of cancers.

PROLINE DERIVATIVES

The invention relates to novel compounds of formula (I), wherein X, Y, R1, R2, R3, R4 and n have the meaning cited in claim 1, are inhibitors of the coagulation factor Xa and can be used for the prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumours.

Phenyl derivatives

Novel compounds of the formula I in which W, X, Y, T, R1 and R2 are as defined in Patent claim 1, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic disorders.