4442-89-1

Upstream product

• 3893-23-0 cyclohexyl phenyl acetonitrile 

Downstream Products

• 90530-95-3 (2-cyclohexyl-2-phenyl-ethyl)-bis-(2-hydroxy-ethyl)-amine 
• 100430-67-9 1-(2-Cyclohexyl-2-phenyl-ethyl)-pyrrolidine-2,5-dione 
• 100366-79-8 1-(2-Cyclohexyl-2-phenyl-ethyl)-5-ethoxy-pyrrolidin-2-one 
• 100366-83-4 (6R,10bR)-6-Cyclohexyl-1,5,6,10b-tetrahydro-2H-pyrrolo[2,1-a]isoquinolin-3-one 
• 100366-84-5 1,5,6,10bα-tetrahydro-6β-cyclohexylpyrrolo<2.1-α>isoquinolin-3(2H)-one 
• 101887-74-5 bis-(2-chloro-ethyl)-(2-cyclohexyl-2-phenyl-ethyl)-amine 
• 55150-60-2 4-cyclohexyl-3,4-dihydroisoquinolin-1(2H)-one 

Relevant academic research and scientific papers

Cobalt-based nanoparticles prepared from MOF-carbon templates as efficient hydrogenation catalysts

The development of efficient and selective nanostructured catalysts for industrially relevant hydrogenation reactions continues to be an actual goal of chemical research. In particular, the hydrogenation of nitriles and nitroarenes is of importance for the production of primary amines, which constitute essential feedstocks and key intermediates for advanced chemicals, life science molecules and materials. Herein, we report the preparation of graphene shell encapsulated Co3O4- and Co-nanoparticles supported on carbon by the template synthesis of cobalt-terephthalic acid MOF on carbon and subsequent pyrolysis. The resulting nanoparticles create stable and reusable catalysts for selective hydrogenation of functionalized and structurally diverse aromatic, heterocyclic and aliphatic nitriles, and as well as nitro compounds to primary amines (>65 examples). The synthetic and practical utility of this novel non-noble metal-based hydrogenation protocol is demonstrated by upscaling several reactions to multigram-scale and recycling of the catalyst.

Anti-viral method

PCT No. PCT/US97/07431 Sec. 371 Date Jan. 6, 1999 Sec. 102(e) Date Jan. 6, 1999 PCT Filed May 2, 1997 PCT Pub. No. WO97/41846 PCT Pub. Date Nov. 13, 1997The present invention provides compounds which inhibit an envelope virus by inhibiting the fusion of the virus with the host cell. The virus may be inhibited in an infected cell, a cell susceptible of infection or a mammal in need thereof.

Urea, thiourea and guanidine compounds and their use as anti-viral agents

The present invention provides compounds which inhibit an envelope virus by inhibiting the fusion of the virus with the host cell. The virus may be inhibited in an infected cell, a cell susceptible of infection or a mammal in need thereof.

Dramatic Reversal of Diastereoselectivity in an N-Acyliminium Ion Cyclization Leading to Hexahydropyrroloisoquinolines. A Case of Competing Steric Interactions

The N-acyliminium ion cyclization 1 -> 2 + 3 (eq 1) with various aliphatic substituents (R = ethyl, cyclohexyl, and tert-butyl) was carried out, as an extension of our work in ref 2.The following 2:3 ratios were obtained: 39:61, 12:88, and 15:85, respecti