444594-32-5

Upstream product

• 79-30-1 isobutyryl chloride 
• 479408-22-5 O⁶-benzyl-8-bromo-3',5'-O-bis(tert-butyldimethylsilyl)-2'-deoxyguanosine 
• 13389-03-2 8-bromo-2'-deoxyguanosine 
• 479408-21-4 3',5'-O,O'-bis(tert-butyldimethylsilyl)-8-bromo-2'-deoxyguanosine 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 444594-39-2 N²-isobutyryl-O⁶-benzyl-8N-(4-bisphenylamino)-3',5'-bis(tert-butyldimethylsilyl)-2'-deoxy-guanosine 
• 444594-35-8 N²-isobutyryl-O⁶-benzyl-8N-(4-methylphenylamino)-3',5'-bis(tert-butyldimethylsilyl)-2'-deoxy-guanosine 
• 444594-36-9 N²-isobutyryl-O⁶-benzyl-8N-(4-methoxyphenylamino)-3',5'-bis(tert-butyldimethylsilyl)-2'-deoxy-guanosine 
• 444594-34-7 N²-isobutyryl-O⁶-benzyl-8N-phenylamino-3',5'-bis(tert-butyldimethylsilyl)-2'-deoxy-guanosine 
• 903905-79-3 N-[6-benzyloxy-9-[4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-8-(1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-ylamino)-9H-purin-2-yl]-isobutyramide 
• 919530-63-5 N²-isobutyryl-8N-phenylamino-2'-deoxyguanosine 
• 919530-65-7 N²-isobutyryl-8N-(4-methylphenylamino)-2'-deoxyguanosine 
• 919530-67-9 N²-isobutyryl-8N-(4-methoxyphenylamino)-2'-deoxy-guanosine 
• 919530-69-1 N²-isobutyryl-8N-(4-bisphenylamino)-2'-deoxyguanosine 
• 919530-64-6 N²-isobutyryl-8N-phenylamino-3',5'-bis(tert-butyldimethylsilyl)-2'-deoxyguanosine 
• 919530-66-8 N²-isobutyryl-8N-(4-methylphenylamino)-3',5'-bis(tert-butyldimethylsilyl)-2'-deoxyguanosine 
• 919530-68-0 N²-isobutyryl-(4-methoxyphenylamino)-3',5'-bis(tert-butyldimethylsilyl)-2'-deoxyguanosine 
• 919530-71-5 N-(9-{5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-6-oxo-8-phenylamino-6,9-dihydro-1H-purin-2-yl)-isobutyramide 
• 919530-70-4 N²-isobutyryl-8N-(4-bisphenylamino)-3',5'-bis(tert-butyldimethylsilyl)-2'-deoxy-guanosine 

Relevant academic research and scientific papers

Highly efficient synthesis of a phosphoramidite building block of C8-deoxyguanosine adducts of aromatic amines

The synthesis of 5′-O-DMTr-3′-O-phosphoramidite-C8-arylamine-dG adducts 11 and 12 is described. The compounds are potential building blocks for the automated synthesis of site-specifically modified oligonucleotides. The C8-adducts were synthesized by a pa

Synthesis and properties of oligonucleotides containing C8-deoxyguanosine arylamine adducts of borderline carcinogens

C8-Arylamine-dG adducts of borderline carcinogens and the bladder and breast carcinogen 4-aminobiphenyl were prepared using cross-coupling chemistry. These adducts were converted into the corresponding C8-arylamine-5′-O- DMTr-2′-deoxyguanosine phosphorami