919530-72-6

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 919530-65-7 N-[6-hydroxy-9-(4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-8-p-tolylamino-9H-purin-2-yl]-isobutyramide 
• 444594-35-8 N²-isobutyryl-O⁶-benzyl-8N-(4-methylphenylamino)-3',5'-bis(tert-butyldimethylsilyl)-2'-deoxy-guanosine 
• 444594-32-5 N²-iso-butyryl-O⁶-benzyl-8-bromo-3',5'-bis-O-(tert-butyldimethylsilyl)-2'-deoxyguanosine 
• 479408-22-5 O⁶-benzyl-8-bromo-3',5'-O-bis(tert-butyldimethylsilyl)-2'-deoxyguanosine 
• 106-49-0 p-toluidine 
• 919530-66-8 N²-isobutyryl-8N-(4-methylphenylamino)-3',5'-bis(tert-butyldimethylsilyl)-2'-deoxyguanosine 
• 919530-65-7 N²-isobutyryl-8N-(4-methylphenylamino)-2'-deoxyguanosine 
• 479408-21-4 3',5'-O,O'-bis(tert-butyldimethylsilyl)-8-bromo-2'-deoxyguanosine 
• 13389-03-2 8-bromo-2'-deoxyguanosine 

Relevant academic research and scientific papers

Synthesis and properties of oligonucleotides containing C8-deoxyguanosine arylamine adducts of borderline carcinogens

C8-Arylamine-dG adducts of borderline carcinogens and the bladder and breast carcinogen 4-aminobiphenyl were prepared using cross-coupling chemistry. These adducts were converted into the corresponding C8-arylamine-5′-O- DMTr-2′-deoxyguanosine phosphorami

Highly efficient synthesis of a phosphoramidite building block of C8-deoxyguanosine adducts of aromatic amines

The synthesis of 5′-O-DMTr-3′-O-phosphoramidite-C8-arylamine-dG adducts 11 and 12 is described. The compounds are potential building blocks for the automated synthesis of site-specifically modified oligonucleotides. The C8-adducts were synthesized by a pa