444663-79-0

Usage

Uses

Used in Pharmaceutical Industry:
1-(2,6-dichlorophenyl)-5-bromo-7-methoxy-3,4-dihydro-2(1H)-quinazolinone is used as an antineoplastic and antiproliferative agent for its potential in cancer research. It targets various cancer cells and shows promise in inhibiting tumor growth and proliferation.
1-(2,6-dichlorophenyl)-5-bromo-7-methoxy-3,4-dihydro-2(1H)-quinazolinone is also used as an anti-inflammatory and analgesic agent due to its potential to alleviate inflammation and pain.
Used in Research and Development:
In the field of research and development, 1-(2,6-dichlorophenyl)-5-bromo-7-methoxy-3,4-dihydro-2(1H)-quinazolinone serves as a valuable compound for studying its biological activities and potential therapeutic applications. Its unique structure and the presence of halogen groups make it an interesting subject for further investigation into its pharmacological properties and possible uses in medicine.

Upstream product

• 444663-77-8 N-[(2,6-dibromo-4-methoxyphenyl)methyl]-N'-(2,6-dichlorophenyl)-N-[(4-methoxyphenyl)methyl]urea 
• 444663-76-7 (2,6-dibromo-4-methoxy-benzyl)-(4-methoxy-benzyl)-amine 
• 130445-13-5 1,3-dibromo-2-(bromomethyl)-5-methoxybenzene 
• 14542-71-3 2,6-dibromo-4-methoxytoluene 
• 444663-78-9 1-(2,6-dichlorophenyl)-3-(4-methoxyphenyl)methyl-5-bromo-7-methoxy-3,4-dihydro-2(1H)-quinazolinone 

Downstream Products

• 444663-88-1 1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)-7-methoxy-3,4-dihydro-2(1H)-quinazolinone 
• 444663-87-0 1-(2,6-dichlorophenyl)-5-(2-chloro-4-fluorophenyl)-7-methoxy-3,4-dihydro-2(1H)-quinazolinone 
• 444664-31-7 4-[1-(2,6-dichloro-phenyl)-5-(2,4-difluoro-phenyl)-2-oxo-1,2,3,4-tetrahydro-quinazolin-7-yl]-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 
• 444664-23-7 trifluoro-methanesulfonic acid 5-(2-chloro-4-fluoro-phenyl)-1-(2,6-dichloro-phenyl)-2-oxo-1,2,3,4-tetrahydro-quinazolin-7-yl ester 
• 503184-98-3 trifluoro-methanesulfonic acid 1-(2,6-dichloro-phenyl)-5-(2,4-difluoro-phenyl)-2-oxo-1,2,3,4-tetrahydro-quinazolin-7-yl ester 
• 444661-91-0 5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-(piperidin-4-ylamino)-3,4-dihydroquinazolin-2(1H)-one 
• 444664-22-6 trifluoro-methanesulfonic acid 5-(2-chloro-phenyl)-1-(2,6-dichloro-phenyl)-2-oxo-1,2,3,4-tetrahydro-quinazolin-7-yl ester 
• 444664-07-7 1-(2,6-dichlorophenyl)-5-(2-chloro-4-fluorophenyl)-7-hydroxy-3,4-dihydro-2(1H)-quinazolinone 
• 444664-05-5 1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)-7-hydroxy-3,4-dihydro-2(1H)-quinazolinone 

Relevant academic research and scientific papers

Design and synthesis of potent, orally bioavailable dihydroquinazolinone inhibitors of p38 MAP kinase

The development of potent, orally bioavailable (in rat) and selective dihydroquinazolinone inhibitors of p38α MAP kinase is described. These analogues are hybrids of a pyridinylimidazole p38α inhibitor reported by Merck Research Laboratories and VX-745. O

(Halo-benzo carbonyl)heterocyclo fused phenyl p38 kinase inhibiting agents

Compounds described by the chemical formula (I) or a pharmaceutically acceptable salt thereof: are inhibitors of p38 useful in the treatment of inflammatory diseases such as arthritis.