446-07-1 Usage
General Description
2'-Fluoro-5'-methylacetophenone is a synthesized organic compound that falls under the chemical class of organic compounds known as aromatic fluorobenzenes. These are essentially compounds containing an aromatic ring where a carbon atom is linked to a fluorine atom. The physical properties of 2'-Fluoro-5'-methylacetophenone dictate that it usually appears as a solid substance that exhibits off-white color. It has applications in various scientific and industrial environments due to its chemical structure and properties. However, as with other synthetic compounds, proper handling and disposal are crucial to avoid any adverse environmental or health implications.
Check Digit Verification of cas no
The CAS Registry Mumber 446-07-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,4 and 6 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 446-07:
(5*4)+(4*4)+(3*6)+(2*0)+(1*7)=61
61 % 10 = 1
So 446-07-1 is a valid CAS Registry Number.
446-07-1Relevant articles and documents
Pd-Catalysed direct C(sp2)-H fluorination of aromatic ketones: Concise access to anacetrapib
Wu, Qiuzi,Mao, Yang-Jie,Zhou, Kun,Wang, Shuang,Chen, Lei,Xu, Zhen-Yuan,Lou, Shao-Jie,Xu, Dan-Qian
supporting information, p. 4544 - 4547 (2021/05/17)
The Pd-cataylsed direct ortho-C(sp2)-H fluorination of aromatic ketones has been developed for the first time. The reaction features good regioselectivity and simple operations, constituting an alternative shortcut to access fluorinated ketones. A concise synthesis of anacetrapib has also been achieved by using late-stage C-H fluorination as a key step.
