446840-31-9

Upstream product

• 446840-29-5 (-)-[(1S,4R)-4-({[tert-butyl(diphenyl)silyl]oxy}methyl)cyclobut-2-enyl]methyl acetate 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 4330-20-5 N-3-benzoylthymine 
• 446840-30-8 (-)-[(1S,4R)-4-({[tert-butyl(diphenyl)silyl]oxy}methyl)cyclobut-2-enyl]methanol 

Downstream Products

• 863485-99-8 (-)-N₁-[(1S,2S,3R,4R)-2,3-dihydroxy-4-(tert-butyl-diphenyl-silyloxymethyl)-cyclobutyl]methyl-5-methyl-1H,3H-pyrimidine-2,4-dione 
• 863485-94-3 (-)-N₁-[(1S,2R,4R)-2-(tert-butyl-diphenyl-silyloxymethyl)-4-hydroxy-cyclobutyl]methyl-5-methyl-1H,3H-pyrimidine-2,4-dione 
• 863485-93-2 (+)-N₁-[(1S,2R,3S)-2-(tert-butyl-diphenyl-silyloxymethyl)-3-hydroxy-cyclobutyl]methyl-5-methyl-1H,3H-pyrimidine-2,4-dione 
• 446840-32-0 1-[4-(tert-butyl-diphenyl-silanyloxymethyl)-cyclobut-2-enylmethyl]-5-methyl-1H-pyrimidine-2,4-dione 

Relevant academic research and scientific papers

A short route to new cyclobutene nucleoside analogues

Nucleoside analogues (+)-4a and (+)-4b were obtained in non-racemic form by a short and efficient way. The key step was a Mitsunobu reaction of alcohol (-)-8 with adenine or protected thymine. The title products were obtained after deprotection steps.