4481-88-3 Usage
Molecular Weight
153.26 g/mol
Chemical Structure
A bicyclic amine with a nitrogen atom within a bicyclic ring system
Functional Groups
Bicyclic ring system
Amino group (-NH2)
Stereochemistry
Contains multiple stereocenters (1aR,2S,4S,5aR,5bS)
Physical State
Likely a solid at room temperature (based on molecular weight and structure)
Solubility
Soluble in organic solvents like ethanol, methanol, and dichloromethane
Reactivity
Can undergo reactions typical of amines, such as alkylation, acylation, and nucleophilic substitution
Uses
Building block for the synthesis of more complex organic compounds
Potential pharmaceutical applications
Under investigation for biological properties
Safety
As with many chemicals, appropriate safety measures should be taken when handling, such as using gloves and eye protection, and working in a well-ventilated area.
Check Digit Verification of cas no
The CAS Registry Mumber 4481-88-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,4,8 and 1 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 4481-88:
(6*4)+(5*4)+(4*8)+(3*1)+(2*8)+(1*8)=103
103 % 10 = 3
So 4481-88-3 is a valid CAS Registry Number.
4481-88-3Relevant academic research and scientific papers
CYANO-PYRIMIDINE INHIBITORS OF EGFR/HER2
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Page/Page column 58-59, (2021/07/17)
Provided herein are compounds, pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat diseases or disorders associated with EGFR and/or HER2 activity.