44976-78-5

Usage

Uses

Used in Research Applications:
(R)-2-acetoxy-3-Methylbutanoic acid is used as a research chemical for [application reason], such as studying its chemical properties, reactivity, or potential applications in various fields.
Used in Synthesis Processes:
In the laboratory, (R)-2-acetoxy-3-Methylbutanoic acid is used as an intermediate or a building block in the synthesis of more complex molecules or compounds, contributing to the development of new materials or pharmaceuticals.

Upstream product

• 108-05-4 vinyl acetate 
• 4026-18-0 2-hydroxy-3-methylbutanoic acid 
• 17407-56-6 (R)-2-Hydroxy-3-methylbutyric acid 
• 108-24-7 acetic anhydride 
• 640-68-6 D-Val-OH 
• 64-19-7 acetic acid 
• 69798-62-5 2-acetoxy-3-methylbutanoic acid 

Downstream Products

• 4216-96-0 (-)-tert-butyl 2-hydroxy-3-methylbutanoate 
• 18671-23-3 N-Benzyloxycarbonyl-N-methyl-L-Val-D-α-hydroxy-isovaleryl-N-methyl-L-Val-D-α-hydroxy-isovaleriansaeure-tert.-butylester 
• 18668-01-4 N-Benzyloxycarbonyl-N-methyl-L-Val-D-α-hydroxy-isovaleriansaeure-tert.-butylester 
• 18668-12-7 N-Benzyloxycarbonyl-N-methyl-L-Val-D-α-hydroxy-isovaleriansaeure 
• 18671-27-7 N-Benzyloxycarbonyl-N-methyl-L-Val-D-α-hydroxy-isovaleryl-N-methyl-L-Val-D-α-hydroxy-isovaleryl-N-methyl-L-Val-D-α-hydroxy-isovaleriansaeure-tert.-butylester 
• 868740-08-3 D-α-Acetoxy-isovaleriansaeure-tert-butylester 

Relevant academic research and scientific papers

Synthesis of citrophilus mealybug sex pheromone using chrysanthemol extracted from Pyrethrum (Tanacetum cinerariifolium)

A commercial pyrethrum extract was used as a source of chrysanthemol for the synthesis of the citrophilus mealybug (Pseudococcus calceolariae) sex pheromone. The chrysanthemic acid esters (pyrethrins I) were isolated and subsequently reduced to obtain chrysanthemol, which was used for ester pheromone synthesis. Field tests showed that the pheromone synthesized using plant-derived chrysanthemol was as attractive to male P. calceolariae as the pheromone obtained using a commercial isomeric chrysanthemol mixture.

Synthesis of optically active α-hydroxy acids by kinetic resolution through lipase-catalyzed enantioselective acetylation

The lipase-catalyzed acetylation of a broad spectrum of racemic 2-hydroxy acids 1 to their 2-acetoxy acids 2 was shown to proceed with high enantioselectivity. Thus, the microbial lipases, in particular from Candida antarctica and Burkholderia species, are convenient biocatalysts for the synthesis of optically active 2-hydroxy acids in excellent enantioselectivity (ee values up to 99%). The absolute configurations of the 2-hydroxy acids 1 were assigned by comparison of the gas-chromatographic data with that of literature-known reference compounds, or by means of the exciton-coupled circular dichroism method (ECCD) on their bichromophoric 2-naphthoate 9-anthrylmethyl derivatives 3. These results establish that (S)-2-hydroxy acids 1 were preferentially acetylated by microbial lipases.