451-45-6

Upstream product

• 599-68-8 N-(4-fluoro-β-hydroxy-phenethyl)-N-methyl-toluene-4-sulfonamide 
• 20805-28-1 5-(4-fluorophenyl)-3-methyloxazolidin-2-one 
• 19338-43-3 5-(4-fluorophenyl)-1,3-oxazolidin-2-one 
• 133962-00-2 1-(4-fluorophenyl)-2-<(N-benzyl-N-methyl)amino>ethanol 
• 74-89-5 methylamine 
• 53617-32-6 2-bromo-1-(4-fluorophenyl)ethan-1-ol 
• 403-29-2 2-bromo-4'-fluoroacetophenone 
• 405-99-2 para-fluorostyrene 
• 332-42-3 (2-bromoethyl)-4-fluorobenzene 
• 450-00-0 1-acetoxy-1-(4-fluoro-phenyl)-2-[methyl-(toluene-4-sulfonyl)-amino]-ethane 
• 456-04-2 2-Chloro-4'-fluoroacetophenone 

Downstream Products

• 864961-02-4 [2-(4-fluorophenyl)-2-hydroxyethyl]methylcarbamic acid t-butyl ester 
• 864961-74-0 5-acetyl-2-amino-thiophene-3-sulfonic acid [2-(4-fluorophenyl)-2-hydroxy-ethyl]-methyl-amide 
• 864961-70-6 (3-{[2-(4-Fluorophenyl)-2-hydroxy-ethyl]-methyl-sulfamoyl}-thiophene-2-yl)-carbamic acid t-butyl ester 
• 864961-78-4 N-(5-Acetyl-3-{[2-(4-fluorophenyl)-2-hydroxy-ethyl]-methyl-sulfamoyl}-thiophene-2-yl)-propionic acid amide 
• 864961-72-8 (5-Bromo-3-{[2-(4-fluorophenyl)-2-hydroxy-ethyl]-methyl-sulfamoyl)-thiophene-2-yl)-carbamic acid t-butyl ester 
• 864961-76-2 (5-bromo-3-{[2-(4-fluorophenyl)-2-hydroxy-ethyl]-methyl-sulfamoyl}-thiophene-2-yl)-methyl-carbamic acid t-butyl ester 
• 864961-73-9 (5-Acetyl-3-{[2-(4-fluorophenyl)-2-hydroxy-ethyl]-methyl-sulfamoyl}-thiophene-2-yl)-carbamic acid t-butyl ester 
• 864961-79-5 N-(5-Acetyl-3-{[2-(4-fluorophenyl)-2-hydroxy-ethyl]-methyl-sulfamoyl}-thiophene-2-yl)-4-fluoro-benzamide 
• 864961-08-0 (2S)-[2-(4-fluorophenyl)-2-hydroxyethyl]methylcarbamic acid t-butyl ester 
• 864961-03-5 [2-azide-2-(4-fluorophenyl)ethyl]methylcarbamic acid t-butyl ester 
• 864961-71-7 C₁₄H₁₄FNO₅S₂ 
• 864961-07-9 (2S)-methoxyphenyl acetic acid (1R)-2-(t-butoxycarbonyl-methylamino)-1-(4-fluorophenyl)ethyl ester 
• 864961-06-8 (2S)-methoxyphenyl acetic acid (1S)-2-(t-butoxycarbonyl-methylamino)-1-(4-fluorophenyl)ethyl ester 
• 864961-69-3 3-{[2-(4-Fluorophenyl)-2-hydroxy-ethyl]-methyl-sulfamoyl}-thiophene-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases

A novel series of 2-aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides have been identified as potent antivirals against human herpesviruses. These compounds demonstrate broad-spectrum inhibition of the herpesvirus polymerases HCMV, HSV-1, EBV, and VZV with high specificity compared to human DNA polymerases.

Heterocyclic compound having oxime group

The present invention provides a compound that has an excellent inhibitory activity on STAT6 activation and is effective against allergic diseases, and a medicinal composition thereof. According to the present invention, disclosed is the compound represented by the General Formula (I) [where R1 and R2 independently represent a C1-6 alkyl group and the like that may have a hydrogen atom or a substituent; R3 represents a C1-6 alkyl group and the like that may have a substituent; R4 and R5 independent represents a hydrogen atom or a C1-6 alkyl group and the like that may have a substituent; R6 represents a hydrogen atom and the like; W represents —SO2— and the like; and X represents a sulphur atom and the like.]or a salt thereof, or a hydrate thereof.

Sulfonyl-containing 3,4-diaryl-3-pyrrolin-2-ones, preparation method, and medical use thereof

The invention relates to sulfonyl-containing 3,4-diaryl-3-pyrrolin-2-ones compounds having formula (I) wherein R1 is selected from the group consisting of 4-methylsulfonyl, 4-aminosulfonyl, hydrogen, 2-, 3-, or 4-halogen, C1-C6