4512-46-3 Usage
General Description
3,3,6,6-tetramethylpiperazine-2,5-dione, also known as 4,4-Dimethyl-2,6-dioxopiperazine, is a chemical compound often used as a crosslinking agent in the production of polymers and resins. It is a cyclic amide that is commonly added to polymer formulations to improve their mechanical and thermal properties. 3,3,6,6-tetramethylpiperazine-2,5-dione is an important building block in the synthesis of polyimides and other high-performance materials due to its ability to form strong covalent bonds with polymer chains. Additionally, 3,3,6,6-tetramethylpiperazine-2,5-dione has shown potential as a drug carrier in pharmaceutical applications, making it a versatile and valuable chemical in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 4512-46-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,5,1 and 2 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4512-46:
(6*4)+(5*5)+(4*1)+(3*2)+(2*4)+(1*6)=73
73 % 10 = 3
So 4512-46-3 is a valid CAS Registry Number.
4512-46-3Relevant articles and documents
Synthesis of cyclopentapeptides with three to five Aib units
Arnhold, Franziska S.,Linden, Anthony,Heimgartner, Heinz
, p. 232 - 244 (2015/03/04)
Four new Aib-containing cyclopentapeptides have been synthesized by cyclization of the corresponding linear pentapeptides using the diethyl phosphorocyanidate (DEPC)/EtN(iPr)2 method. The linear precursors were prepared via the 'azirine/oxazolo
3-(Dimethylamino)-2,2-dimethyl-2H-azirine as an Aib Equivalent; Synthesis of Aib Oligopeptides
Obrecht, Daniel,Heimgartner, Heinz
, p. 102 - 115 (2007/10/02)
3-(Dimethylamino)-2,2-dimethyl-2H-azirine (1) reacts with carboxylic acids at 0-25 degC to give 2-acylamino-N,N,2-trimethylpropionamides (=2-acylamino-N,N-dimethylisobutyramide, acyl-Aib-NMe2) in excellent yields (Scheme 2 and 3).Examples of α-amino-, α-h
