45124-35-4Relevant academic research and scientific papers
Joint Synthesis of Tertiary Unsymmetrical and Symmetrical Aliphatic Amines
Kozlov,Tereshko,Basalaeva,Tarasevich
, p. 1095 - 1098 (2007/10/03)
Tertiary unsymmetrical and symmetrical aliphatic amines were prepared by reaction of higher (C8-C16) and lower (C2-C4) aliphatic alcohols with nitriles containing the same number of carbon atoms as the lower aliphatic alcohols. Reaction conditions ensuring nearly quantitative yields of tertiary amines were determined.
Carbon monoxide as a building block in organic synthesis IV. Direct preparation of amines from alkenes by aminomethylation catalysed by dinuclear rhodium complexes
Baig, Thierry,Molinier, Jacques,Kalck, Philippe
, p. 219 - 224 (2007/10/02)
The one-pot aminomethylation reaction has been performed under low pressures of carbon monoxide and hydrogen in the presence of the complex tBu)2(CO)2(PPh3)2>.This reaction involves the successive hydroformylation of the alkene, the condensation of the aldehyde produced in the first step with the amine, and the hydrogenation of the imine or enamine thus obtained.This last hydrogenation step is rate-determining.At 1.8 MPa, oct-1-ene was transformed with 99percent conversion, giving 80percent diethylnonylamine, 2percent of the iso-compound and 13percent methyl-2-octanal, which is more resistant to the condensation with diethylamine and further hydrogenation.
One-pot Synthesis of Amines by Aminomethylation of Alkenes catalysed by Dinuclear Rhodium Complexes under Mild Conditions
Baig, Thierry,Kalck, Philippe
, p. 1373 - 1374 (2007/10/02)
The complex t)2(CO)2(PPh3)2> with a slight excess of PPh3 catalyses the aminomethylation reaction of terminal alkenes under low pressures of carbon monoxide and hydrogen.
