4514-52-7 Usage
Uses
Used in Pharmaceutical Industry:
1-(3-bromophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine is used as an intermediate in the synthesis of various pharmaceuticals. Its chemical structure allows for modification to create molecules with desired properties for specific medical applications.
Used in Agrochemical Industry:
1-(3-bromophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine also serves as an intermediate in the synthesis of agrochemicals, where its unique structure can be tailored to develop effective products for agricultural use.
Used in Dye Industry:
1-(3-bromophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine is used in the production of dyes, where its chemical composition contributes to the development of new and improved dye formulations.
Check Digit Verification of cas no
The CAS Registry Mumber 4514-52-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,5,1 and 4 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 4514-52:
(6*4)+(5*5)+(4*1)+(3*4)+(2*5)+(1*2)=77
77 % 10 = 7
So 4514-52-7 is a valid CAS Registry Number.
4514-52-7Relevant academic research and scientific papers
Synthesis and in vitro evaluation of 2,4-diamino-1,3,5-triazine derivatives as neuronal voltage-gated sodium channel blockers
Ma, Xiang,Poon, Thong-Yuen,Wong, Peter Tsun Hon,Chui, Wai-Keung
supporting information; experimental part, p. 5644 - 5647 (2010/04/26)
Neuronal sodium channels blockers interfere with ion flux and have been used for managing neuropathic pain, epilepsy, and cerebral ischemic disorders. In the current study, four groups of 2,4-diamino-1,3,5-triazine derivatives were synthesized and investigated for their neuronal sodium channels binding activity. 5-Aryl-1,3,5-triazaspiro[5.5]undeca-1,3-diene-2,4-diamines (4a-4j) were found to have the best neuronal sodium binding activity among the four groups of triazines evaluated. Derivatives 4a-4j blocked the sodium channels with IC50 values ranged from 4.0 to 14.7 μM. The result from this study showed that analogues of 2,4-diamino-1,3,5-triazines could be used as leads for the discovery of neuronal sodium channels blockers for managing central nervous system related disorders.
