452921-71-0

Basic information

• Product Name: 1-benzyloxy-3-nitro-5,6,7,8-tetrahydronaphthalene
• Synonyms: 1-benzyloxy-3-nitro-5,6,7,8-tetrahydronaphthalene
• CAS NO: 452921-71-0
• Molecular Weight: 283.327
• Mol File: 452921-71-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-benzyloxy-3-nitro-5,6,7,8-tetrahydronaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyloxy-3-nitro-5,6,7,8-tetrahydronaphthalene(452921-71-0)
• EPA Substance Registry System: 1-benzyloxy-3-nitro-5,6,7,8-tetrahydronaphthalene(452921-71-0)

Safety Data

• Hazardous Substances Data: 452921-71-0(Hazardous Substances Data)

Upstream product

• 50536-99-7 3-nitro-5,6,7,8-tetrahydro-[1]naphthylamine 
• 51522-30-6 5,7-dinitro-1,2,3,4-tetrahydronaphthalene 
• 119-64-2 tetralin 
• 452921-70-9 1-hydroxy-3-nitro-5,6,7,8-tetrahydronaphthalene 
• 100-39-0 benzyl bromide 

Downstream Products

• 452921-85-6 (4-benzyloxy-1-iodo-5,6,7,8-tetrahydro-naphthalen-2-yl)-(3-chloro-but-2-enyl)-carbamic acid tert-butyl ester 
• 452921-84-5 (4-benzyloxy-1-iodo-5,6,7,8-tetrahydro-naphthalen-2-yl)-(3-chloro-allyl)-carbamic acid tert-butyl ester 
• 452921-72-1 5-benzyloxy-3-(tert-butyloxycarbonyl)-1-chloromethyl-1,2,6,7,8,9-hexahydro-3H-benz[e]indole 
• 452921-69-6 4-benzyloxy-2-(tert-butyloxycarbonylamino)-1-iodo-5,6,7,8-tetrahydronaphthalene 
• 452921-83-4 1-benzyloxy-3-(tert-butyloxycarbonylamino)-5,6,7,8-tetrahydronaphthalene 
• 452921-82-3 3-amino-1-benzyloxy-5,6,7,8-tetrahydronaphthalene 

Relevant articles and documents

Synthesis and biological evaluation of novel analogues and prodrugs of the cytotoxic antibiotic CC-1065 for selective cancer therapy

This paper describes novel seco-analogues 25-27 of the cytotoxic antibiotic CC-1065 (1) and their prodrugs 5, 6a, and 6b, for antibody-directed enzyme prodrug therapy (ADEPT). The partially hydrogenated seco-CCI-analogue 7 and the corresponding methyl-CCI