51522-30-6Relevant academic research and scientific papers
COMPOUNDS THAT MODULATE EGFR ACTIVITY AND METHODS FOR TREATING OR PREVENTING CONDITIONS THEREWITH
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Page/Page column 79, (2011/11/30)
Provided are compounds and methods for treating or preventing kinase-mediated disorders therewith.
Synthesis and biological evaluation of novel analogues and prodrugs of the cytotoxic antibiotic CC-1065 for selective cancer therapy
Tietze, Lutz F.,Herzig, Tobias,Feuerstein, Tim,Schuberth, Ingrid
, p. 1634 - 1645 (2007/10/03)
This paper describes novel seco-analogues 25-27 of the cytotoxic antibiotic CC-1065 (1) and their prodrugs 5, 6a, and 6b, for antibody-directed enzyme prodrug therapy (ADEPT). The partially hydrogenated seco-CCI-analogue 7 and the corresponding methyl-CCI
