454186-01-7

Upstream product

• 2973-78-6 3-bromo-4-hydroxybenzylaldehyde 
• 52783-74-1 (3-bromo-4,5-dimethoxyphenyl)methanol 
• 6948-30-7 5-bromoveratralaldehyde 
• 123-08-0 4-hydroxy-benzaldehyde 
• 147283-85-0 (4-Trifluoromethanesulfonyloxy-phenyl)-acetic acid methyl ester 
• 454186-08-4 (3-bromo-4-isopropoxyphenyl)methanol 
• 191602-84-3 3-bromo-4-iso-propoxybenzaldehyde 
• 121-33-5 vanillin 
• 5320-34-3 3,4-Dimethoxy-5-benzyloxyphenylaceticacid 
• 7632-64-6 3-benzyloxy-4,5-dimethoxyphenylacetonitrile 
• 14199-15-6 Methyl 4-hydroxyphenylacetate 
• 2973-76-4 5-bromo-4-hydroxy-3-methoxybenzaldehyde 
• 7632-62-4 3-benzyloxy-4,5-dimethoxybenzyl alcohol 
• 454186-00-6 N-[2-(3-benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-2-[4-(5-formyl-2-isopropoxy-phenoxy)-phenyl]-N-(1-phenyl-ethyl)-acetamide 

Downstream Products

• 454186-12-0 3-(4-{[[2-(3-Benzyloxy-4,5-dimethoxy-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-carbamoyl]-methyl}-phenoxy)-4-isopropoxy-benzoic acid methyl ester 
• 454186-06-2 8-{4-[2-(ethoxycarbonyl-methyl-amino)-ethyl]-2-nitro-phenoxy}-1-[4-(2-isopropoxy-5-methoxycarbonyl-phenoxy)-benzyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester 
• 454185-87-6 3-[4-((S)-8-{4-[2-(Ethoxycarbonyl-methyl-amino)-ethyl]-2-methoxy-phenoxy}-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-1-ylmethyl)-phenoxy]-4-isopropoxy-benzoic acid methyl ester 
• 454186-14-2 3-{4-[(S)-6,7-Dimethoxy-8-(6-methoxy-2-methyl-1-oxo-1,2,3,4-tetrahydro-isoquinolin-7-yloxy)-2-methyl-1,2,3,4-tetrahydro-isoquinolin-1-ylmethyl]-phenoxy}-4-isopropoxy-benzoic acid methyl ester 
• 454186-03-9 3-{4-[(S)-8-Benzyloxy-6,7-dimethoxy-2-((S)-1-phenyl-ethyl)-1,2,3,4-tetrahydro-isoquinolin-1-ylmethyl]-phenoxy}-4-isopropoxy-benzoic acid methyl ester 
• 454185-88-7 8-hydroxy-1-[4-(2-isopropoxy-5-methoxycarbonyl-phenoxy)-benzyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

First enantioselective total synthesis of (-)-tejedine

(Matrix presented) The first enantioselective total synthesis of (-)-tejedine (1) is reported. Tejedine is a seco-bisbenzyltetrahydroisoquinoline isolated in 1998 as a minor component from Berberis vulgaris. The synthesis was achieved using a strategy employing four key steps, including a chiral auxiliary-assisted diastereoselective Bischler-Napieralski cyclization.