454185-91-2Relevant articles and documents
First enantioselective total synthesis of (-)-tejedine
Wang, You-Chu,Georghiou, Paris E.
, p. 2675 - 2678 (2007/10/03)
(Matrix presented) The first enantioselective total synthesis of (-)-tejedine (1) is reported. Tejedine is a seco-bisbenzyltetrahydroisoquinoline isolated in 1998 as a minor component from Berberis vulgaris. The synthesis was achieved using a strategy employing four key steps, including a chiral auxiliary-assisted diastereoselective Bischler-Napieralski cyclization.