4543-66-2

Usage

Uses

The Dodecanedinitrile could react with C-tert-butoxy-tetra-N-methyl-methanediamine to obtain the 2-(Dimethylaminomethylen)dodecansaeuredinitril.

Synthesis Reference(s)

The Journal of Organic Chemistry, 36, p. 3050, 1971 DOI: 10.1021/jo00819a035

InChI:InChI=1/C12H20N2/c13-11-9-7-5-3-1-2-4-6-8-10-12-14/h1-10H2

Upstream product

• 5602-19-7 6-cyanohexanaoic acid 
• 6948-45-4 11-bromoundecanenitrile 
• 151-50-8 potassium cyanide 
• 693-23-2 1,12-dodecanedioic acid 
• 4101-68-2 1,10-dibromodecane 
• 2162-98-3 1,10-dichlorodecane 
• 143-33-9 sodium cyanide 
• 2783-17-7 1,12-Diaminododecane 
• 137042-72-9 C₁₃H₂₃BrN₂O 
• 2467-10-9 1,1,1,5-tetrachloropentane 
• 90943-97-8 1,5,5,6,6,10-hexachloro-decane 
• 63616-36-4 1,5,6,10-tetrachloro-dec-5-ene 
• 6224-99-3 1,10-decanedicarboxamide 
• 646-25-3 diaminodecane 

Downstream Products

• 2783-17-7 1,12-Diaminododecane 
• 693-23-2 1,12-dodecanedioic acid 
• 1731-79-9 dodecanedioic acid dimethyl ester 
• 6224-99-3 1,10-decanedicarboxamide 
• 38300-52-6 cyclodocosane-1,12-dione 
• 5675-51-4 1,12-dodecandiol 
• 3344-70-5 1,12-dibromododecane 

Relevant academic research and scientific papers

Method for catalyzing receptor-free dehydrogenation of primary amine to generate nitrile by Ru coordination compound

The invention discloses a method for catalyzing receptor-free dehydrogenation of primary amine to generate nitrile by a Ru coordination compound. The method comprises: adding a Ru coordination compound, an alkali, a primary amine and an organic solvent into a reaction test tube according to a mol ratio of 1:100:(100-500):1000-3000, and carrying out a stirring reaction under the condition of 80 to120 DEG C; and when gas chromatography monitors that the raw materials completely disappear, stopping the reaction, collecting the reaction solution, centrifuging the reaction solution, taking the supernatant, extracting with dichloromethane, merging the organic phases, drying, filtering, evaporating the organic solvent under reduced pressure to obtain a filtrate, and carrying out column chromatography purification on the filtrate to obtain the target product nitrile. According to the invention, the catalyst is good in activity, single in catalytic system, good in product selectivity, simple in subsequent treatment and good in system universality after the reaction is finished, has a good catalytic effect on various aryl, alkyl and heteroaryl substituted primary amines, and also has a gooddehydrogenation performance on secondary amines.

Corresponding amine nitrile and method of manufacturing thereof (by machine translation)

The present invention relates to a nitrile manufacturing method, which has characteristics of significantly-reduced ammonia source consumption, low environmental pressure, low energy consumption, low production cost, high nitrile purity, high nitrile yield and the like compared with the method in the prior art, wherein nitrile having a complicated structure can be obtained through the method. The present invention further relates to a method for producing a corresponding amine from the nitrile.

Corresponding amine nitrile and method of manufacturing thereof

The invention relates to a preparation method of nitrile. Compared with the prior art, the preparation method has the characteristics of obvious reduction of the usage amount of ammonia sources, low environmental pressure, low energy consumption, low production cost, high purity and yields of nitrile products, and the like, and can be used for obtaining nitrile with a more complex structure. The invention also relates to a method for preparing corresponding amine with nitrile.

Corresponding amine nitrile and method of manufacturing thereof

The invention relates to a preparation method of nitrile. Compared with the prior art, the preparation method has the characteristics of obvious reduction of the usage amount of ammonia sources, low environmental pressure, low energy consumption, low production cost, high purity and yields of nitrile products, and the like, and can be used for obtaining nitrile with a more complex structure. The invention also relates to a method for preparing corresponding amine with nitrile.

Method for producing compounds comprising nitrile functions

The present invention concerns the production of compounds comprising nitrite functions and cyclic imide compounds. More specifically, the invention relates to the production of compounds comprising nitrile functions from compounds comprising carboxylic functions, advantageously of natural and renewable origin, and from methyl-2 glutaronitrile (MGN) or a mixture N of dinitriles comprising methyl-2 glutaronitrile (MGN), ethyl-2 succinonitrile (ESN) and adiponitrile (AdN).

USE OF COMPOUNDS WITH NITROGEN-CONTAINING FUNCTIONAL GROUPS FOR THERMAL ENERGY STORAGE

The present invention relates to the use of a compound consisting of a linear saturated C8-C24 hydrocarbon-based chain bearing at each end a nitrogen-containing functional group, other than —NH2, for the storage of thermal energy. It also relates to a process for the storage and optionally for the release of thermal energy, comprising the contacting of a wall to be cooled with a first heat transfer fluid then of said first heat transfer fluid with a material comprising said compound and optionally the contacting of said material with a second heat transfer fluid then of said second heat transfer fluid with a wall to be heated.

Ni-catalyzed reductive homocoupling of unactivated alkyl bromides at room temperature and its synthetic application

A room-temperature Ni-catalyzed reductive approach to homocoupling of unactivated primary, secondary, and tertiary alkyl bromides is described. The catalytic system can be easily generated from air-stable and cheap materials and demonstrates broad functional group tolerance, thus allowing facile access to useful dimeric triterpene and lignan-like molecules. Moreover, the dimerization of tertiary bromide 6 efficiently establishes sterically hindered vicinal quaternary carbons (C3a and C3a′), which is a key linkage of intriguing bispyrrolo[2,3-b]indoline alkaloids, thereby enabling us to complete the total syntheses of racemic chimonanthine (9) and folicanthine (10). In addition, this dimerization method can be expanded to the highly stereoselective synthesis of bisperhydrofuro[2,3-b]furan (5a) and the dimeric spiroketal 5b, signifying the involvement of possible radical species.

Direct and facile oxidative conversion of primary, secondary, and tertiary amines to their corresponding nitriles

Molecular iodine in aqueous ammonia at 60 °C efficiently oxidized various primary, secondary, and tertiary amines to their corresponding nitriles in good yields. Georg Thieme Verlag Stuttgart.

A new synthesis of nitriles from N-alkoxyimidoyl halides with zinc

Both aliphatic and aromatic nitriles are obtained from the corresponding N-methoxy-, N-benzyloxy- or N-tert-butoxyimidoyl halides with zinc in a acetic acid/dimethylformamide mixture (1:1).