2162-98-3Relevant articles and documents
OZONOLYTIC CLEAVAGE OF CYCLOALKENES TO TERMINALLY DIFFERENTIATED PRODUCTS
Cardinale, G.,Grimmelikhuysen, J. C.,Laan, J. A. M.,Ward, J. P.
, p. 1881 - 1884 (1984)
A method is described by which alkoxy hydroperoxides, obtained by ozonising cycloalkenes in alcohol solution, can be converted into terminally differentiated products by the action of metal salts.Cyclohexene and cycloheptene were converted to 1,1-dimethoxy-5-chloropentane and 1,1-dimethoxy-6-chlorohexane respectively in 47percent yield, using ferric chloride.With ferrous sulphate as reactant salt, cyclooctene was converted into 1,1-dimethoxy-6-heptene.A synthesis of (Z)-4-heptenal from (Z,Z)-1,5-cyclooctadiene is also described.Fragmentation, causing the loss of one carbon atom, is a characteristic of these transformations.Other variations employed the salts as oxidants and reductants simultaneously.
Cobalt-Catalyzed Csp3?Csp3Homocoupling
Cai, Yingxiao,Qian, Xin,Gosmini, Corinne
supporting information, p. 2427 - 2430 (2016/08/16)
An efficient and easy method for Csp3?Csp3homocoupling was developed using cobalt bromide as catalyst. A series of functionalized alkyl bromides and alkyl chlorides were coupled in high yields under mild conditions. This reaction seems to involve a radical intermediate. (Figure presented.).
Characterization of polychlorinated alkane mixtures - A Monte Carlo modeling approach
Jensen, Soren R.,Brown, Wayne A.,Heath, Ester,Cooper, David G.
, p. 703 - 717 (2008/02/13)
A Monte Carlo model was developed to characterize the molecular composition of polychlorinated alkane mixtures. The model is based upon a simulation of the free-radical chlorination process by which polychlorinated alkane mixtures are produced industrially from n-alkanes. In the model, the free-radical chlorination reaction was simulated by randomly selecting a position on a partially converted alkane molecule for target by chlorine free-radical attack. The relative reactivities of the hydrogen atoms on the alkane chain towards chlorine free-radical substitution were either determined experimentally or extrapolated from experimental results and incorporated into the model. The result of the simulation is the prediction of the detailed molecular composition of any PCA mixture. Good agreement was found when comparing the distribution of molecules predicted by the model to analytically determined distributions of real PCA mixtures. Results from the model were then coupled with rules describing the action of biological enzymes to estimate the upper limit possible for the aerobic biodegradation of PCA mixtures.
The synthesis of phosphates of long-chain ω-hydroxyalkyl esters of 11-deoxyprostaglandin E1
Sokolov,Turovskii,Lukevits
, p. 62 - 64 (2007/10/03)
Di(p-methylbenzyl) phosphates of ω-hydroxyalkyl esters of 11-deoxyprostaglandin E1 were synthesized from disubstituted 1,10-decane and 1,22-docosane derivatives for studying the permeability of bilayer membranes.