454437-24-2

Upstream product

• 337519-98-9 3-((E)-3-{4-[1-(t-butoxycarbonyl)piperidin-4-yloxy]phenylamino}-1-propenyl)benzonitrile 
• 100-02-7 4-nitro-phenol 
• 24964-64-5 3-Cyanobenzaldehyde 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 
• 98116-49-5 3-cyano-1-(2-formylethenyl)benzene 
• 138227-63-1 tert-butyl 4-(4-aminophenoxy)piperidine-1-carboxylate 
• 138227-62-0 tert-butyl 4-(4-nitrophenoxy)piperidine-1-carboxylate 

Relevant academic research and scientific papers

The discovery of YM-60828: a potent, selective and orally-bioavailable factor Xa inhibitor.

Since Factor Xa (FXa) is well known to play a central role in thrombosis and hemostasis, inhibition of FXa is an attractive target for antithrombotic strategies. As a part of our investigation of a non-peptide, orally available FXa inhibitor, we found tha