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Bis(4-methoxyphenyl)iodonium trifluoroacetate is a chemical compound with the formula C18H15IO2F3. It is a type of iodonium salt, which is a class of compounds containing a positively charged iodine atom. This specific compound is characterized by two 4-methoxyphenyl groups attached to the iodine atom, and a trifluoroacetate anion. It is often used as a reagent in organic synthesis, particularly in the formation of carbon-carbon bonds through a process known as the iodine(III)-mediated coupling reaction. The trifluoroacetate anion provides a stable counterion, which helps to stabilize the overall structure of the compound. Its applications in chemistry make it a valuable tool for researchers and chemists working on various organic transformations.

457-66-9

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457-66-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 457-66-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,5 and 7 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 457-66:
(5*4)+(4*5)+(3*7)+(2*6)+(1*6)=79
79 % 10 = 9
So 457-66-9 is a valid CAS Registry Number.

457-66-9Relevant academic research and scientific papers

Palladium-Catalyzed Four-Component Carbonylative Cyclization Reaction of Trifluoroacetimidoyl Chlorides, Propargyl Amines, and Diaryliodonium Salts: Access to Trifluoromethyl-Containing Trisubstituted Imidazoles

Chen, Zhengkai,Wang, Wei-Feng,Yang, Hefei,Wu, Xiao-Feng

supporting information, p. 1980 - 1984 (2020/03/04)

A palladium-catalyzed four-component carbonylative cyclization reaction for the expeditious construction of trifluoromethyl-containing trisubstituted imidazoles has been achieved. With readily accessible trifluoroacetimidoyl chlorides, propargyl amines, a

Platinum-catalyzed C-H arylation of simple arenes

Wagner, Anna M.,Hickman, Amanda J.,Sanford, Melanie S.

supporting information, p. 15710 - 15713 (2013/11/06)

This report describes the Na2PtCl4 catalyzed C-H arylation of arene substrates with diaryliodonium salts. The site selectivity of these reactions is predominantly controlled by steric factors. Remarkably, Na2PtCl4-catalyzed naphthalene arylation proceeds with opposite site selectivity compared to that obtained with Na2PdCl 4 as the catalyst. Preliminary mechanistic studies provide evidence for a PtII/PtIV catalytic cycle involving rate-limiting C-C bond-forming reductive elimination.

One-pot synthesis of diaryliodonium salts using toluenesulfonic acid: A fast entry to electron-rich diaryliodonium tosylates and triflates

Zhu, Mingzhao,Jalalian, Nazli,Olofsson, Berit

, p. 592 - 596 (2008/12/22)

A direct synthesis of symmetric and unsymmetric electron-rich diaryliodonium salts is described. The use of MCPBA and toluenesulfonic acid delivers diaryliodonium tosylates in high yields. An in situ anion exchange has also been developed, giving access to the corresponding triflate salts. Georg Thieme Verlag Stuttgart.

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