4572-26-3

Basic information

• Product Name: Spiro[furan-2(3H),1'-[2,5]cyclohexadiene]-4',5(4H)-dione
• Synonyms: 1-Oxaspiro[4.5]decane-6,9-diene-2,8-dione;Spiro[furan-2(3H),1'-[2,5]cyclohexadiene]-4',5(4H)-dione
• CAS NO: 4572-26-3
• Molecular Formula: C₉H₈O₃
• Molecular Weight: 164.16
• Mol File: 4572-26-3.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Spiro[furan-2(3H),1'-[2,5]cyclohexadiene]-4',5(4H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: Spiro[furan-2(3H),1'-[2,5]cyclohexadiene]-4',5(4H)-dione(4572-26-3)
• EPA Substance Registry System: Spiro[furan-2(3H),1'-[2,5]cyclohexadiene]-4',5(4H)-dione(4572-26-3)

Safety Data

• Hazardous Substances Data: 4572-26-3(Hazardous Substances Data)

Upstream product

• 501-97-3 4-hydroxyphenylpropionic acid 
• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 291313-34-3 methyl 3-(4-hydroxyphenyl)propionate-benzylimide 
• 5597-50-2 3-(4-hydroxyphenyl)propionic acid methyl ester 
• 67-56-1 methanol 

Downstream Products

• 528-43-8 Magnolol 
• 112639-25-5 2,2'-dihydroxy-5-methyl-5'-(2-methoxycarbonylethyl)biphenyl 
• 163015-44-9 C₂₆H₂₈O₄ 
• 1431318-95-4 C₂₀H₁₉NO₅ 
• 1431318-82-9 (1'S,2S,3'R,3a'S,7a'R)-methyl 1'-cyclohexyl-5,7'-dioxo-1',2',3',3a',4,5,7',7a'-octahydro-3H-spiro[furan-2,4'-isoindole]-3'-carboxylate 
• 1431318-94-3 (1'S,2S,3'R,3a'S,7a'R)-methyl 3'-benzyl-5,7'-dioxo-1'-phenyl-1',2',3',3a',4,5,7',7a'-octahydro-3H-spiro[furan-2,4'-isoindole]-3'-carboxylate 
• 1431318-93-2 (1'S,2S,3'R,3a'S,7a'R)-methyl 3'-isobutyl-5,7'-dioxo-1'-phenyl-1',2',3',3a',4,5,7',7a'-octahydro-3H-spiro[furan-2,4'-isoindole]-3'-carboxylate 
• 1431318-92-1 (1'S,2S,3'R,3a'S,7a'R)-methyl 5,7'-dioxo-1'-phenyl-3'-propyl-1',2',3',3a',4,5,7',7a'-octahydro-3H-spiro[furan-2,4'-isoindole]-3'-carboxylate 
• 1431318-91-0 (1'S,2S,3'R,3a'S,7a'R)-methyl 3'-ethyl-5,7'-dioxo-1'-phenyl-1',2',3',3a',4,5,7',7a'-octahydro-3H-spiro[furan-2,4'-isoindole]-3'-carboxylate 
• 1431318-89-6 (1'S,2S,3'R,3a'S,7a'R)-methyl 3'-methyl-5,7'-dioxo-1'-(o-tolyl)-1',2',3',3a',4,5,7',7a'-octahydro-3H-spiro[furan-2,4'-isoindole]-3'-carboxylate 
• 1431318-88-5 (1'S,2S,3'R,3a'S,7a'R)-methyl 3'-methyl-5,7'-dioxo-1'-(p-tolyl)-1',2',3',3a',4,5,7',7a'-octahydro-3H-spiro[furan-2,4'-isoindole]-3'-carboxylate 
• 1431318-87-4 (1'S,2S,3'R,3a'S,7a'R)-methyl 3'-methyl-5,7'-dioxo-1'-phenyl-1',2',3',3a',4,5,7',7a'-octahydro-3H-spiro[furan-2,4'-isoindole]-3'-carboxylate 

Relevant articles and documents

Palladium-Catalyzed Directed para C?H Functionalization of Phenols

Various practical methods for the selective C?H functionalization of the ortho and recently also of the meta position of an arene have already been developed. Following our recent development of the directing-group-assisted para C?H functionalization of toluene derivatives, we herein report the first remote para C?H functionalization of phenol derivatives by using a recyclable silicon-containing biphenyl-based template. The effectiveness of this strategy was illustrated with different synthetic elaborations and by the synthesis of various phenol-based natural products.

New oxidative transformations of phenolic and indolic oxazolines: An avenue to useful azaspirocyclic building-blocks

The oxidative cyclization of a phenolic amide to a spirolactam has long been regarded as an 'impossible' reaction, because exposure of the substrates to a variety of oxidants results in formation of spirolactones with consequent loss of the amine segment. We recently communicated that this heretofore unknown transformation may be achieved by oxidation of oxazoline analogues of phenolic and indolic amides. Herein, we provide full details of our work.