457628-23-8

Upstream product

• 18278-34-7 4-hydroxy-2-methoxybenzaldehyde 
• 358-23-6 trifluoromethylsulfonic anhydride 
• 95-01-2 2,4-Dihydroxybenzaldehyde 
• 156001-73-9 trifluoromethanesulfonic acid 4-formyl-3-methoxyphenyl ester 

Downstream Products

• 635679-15-1 2-hydroxy-4-[5-(4-methyl-2,5-bis-trimethylsilanylethynyl-phenyl)-thiophen-2-yl]-benzaldehyde 
• 635679-16-2 4-[5-(2,5-diethynyl-4-methyl-phenyl)-thiophen-2-yl]-2-hydroxy-benzaldehyde 
• 635679-10-6 4-[5-(2,5-diethynyl-4-methyl-phenyl)-thiophen-2-yl]-2-triisopropylsilanyloxy-benzaldehyde 
• 457628-24-9 trifluoro-methanesulfonic acid 3-allyloxy-4-formyl-phenyl ester 
• 791068-99-0 4-ethynyl-2-hydroxybenzaldehyde 
• 1191396-93-6 C₄₀H₄₆O₆ 
• 791068-95-6 4-trimethylsilylacetylenesalicylaldehyde 

Relevant academic research and scientific papers

Triazacoronene Derivatives with Three peri-Benzopyrano Extensions: Synthesis, Structure, and Properties

New π-extended triazacoronene derivatives containing three peri-benzopyrano extensions were successfully synthesized through tandem triflic acid catalyzed threefold Pictet–Spengler cyclization and K2CO3-catalyzed ipso-aromatic substi

Fluorescent non-linear chiral polymer chemosensor bonded alternatively with 1,4-diethynyl-2,5-dioctyloxybenzene and (R,R)-salen for Zn 2+recognition

Stereoregular non-linear chiral main chain polymers 1a-b bonded alternatively with (R,R)-salen and 1,4-diethynyl-2,5-dioctyloxybenzene moieties have been synthesized using palladium catalyzed C-C cross-coupling and Schiff base formation reactions as the k

Fluorescent OFF-ON polymer chemosensor bonded alternatively with 1,4-dioctyloxybenzene and (R,R)-salen for cascade Zn2+ and chiral recognition

The synthesis of the chiral main chain polymers 1a-b bonded alternatively with (R,R)-salen and 1,4-dioctyloxybenzene has been described employing a palladium-catalyzed C-C cross-coupling reaction as the key step. They are soluble in common organic solvent

NON-NUCLEOTIDE REVERSE TRANSCRIPTASE INHIBITORS

Compounds of the formula Z: where; A is CH or N; R1 is a substituent to a carbon atom in the ring containing A selected from -S(=O)pRa, where Ra is -C1-C4 alkyl, -ORx, -NRxRx, -NHNRxRx, - NHNHC(=O)ORx, -NRxOH; -C(=O)-Rb, where Rb is -CT-C4-alkyl, ORx, -NRxRx, -NHNRxRx, -NHC1-C3-alkyl-C(=O)Orx -NRxRc, where Rc is H, C1-C4 alkyl, -NRxRx; -C(=0)Rd, -CN, S(=O)pRx where Rd is Rd is C1-C4-alkyl, -ORx, -NRxRx C1-C3-alkyl-O-Cl-C3alkylC(=O)ORx, -C1-C3-alkyl-COORx; -C1-C3alkyl-OH or C1-C4 alkyl ethers or esters thereof (O-Cl-C3alkyl)q-O-Rx a 5 or 6 membered aromatic ring having 1-3 hetero atoms p is 1 or 2; Rx is independently selected from H, C1-C4 alkyl or acetyl; or a pair of Rx can together with the adjacent N atom form a ring; L is -0-, -S(=O),- or -CH2-, where r is 0, 1 or 2; R3-R7 are substituents as defined in the specification; X is -(CR8R8')n-D-(CR8R8')m-; D is a bond, -NR9-, -0-, -S-, -S(=0)- or -S(=0)2-; and pharmaceutically acceptable salts and prodrugs thereof, have utility as HIV antivirals.

A Fluorescent Self-Amplifying Wavelength-Responsive Sensory Polymer for Fluoride Ions

A glowing response: Novel fluoride-selective sensors, utilizing fluoride-induced lactonization to highly fluorescent coumarin derivatives, are reported. The incorporation of this sensory system into a conjugated polymer amplifies the fluorescence response

Non-nucleoside reverse transcriptase inhibitors

Compounds of the formula I: where; R1 is O, S; R2 is an optionally substituted nitrogen-containing heterocycle, wherein the nitrogen is located at the 2 position relative to the (thio)urea bond; R3 is H, C1-C3 alkyl, R4-R7 are independently selected from H, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, haloC1-C6 alkyl, C1-C6 alkanoyl, haloC1-C6 alkanoyl, C1-C6 alkoxy, haloC1-C6 alkoxy, C1-C6 alkyloxy-C1-C6 alkyl, haloC1-C6 alkyloxy-C1-C6 alkyl hydroxy-C1-C6 alkyl, amino-C1-C6 alkyl, carboxy-C1-C6 alkyl, cyano-C1-C6 alkyl, amino, carboxy, carbamoyl, cyano, halo, hydroxy, keto; X is —(CHR8)n-—D—(CHR8)m—; D is —NR9—, —O—, —S—, —S(═O)— or —S(═O)2—; R8 is independently H, C1-C3 alkyl, halo substitutedC1-C3alkyl; R9 is H, C1-C3 alkyl; n and m are independently 0, 1 or 2; and prodrugs and pharmaceutically acceptable salts thereof, have utility as inhibitors of HIV-1 reverse transcriptase, particularly drug escape mutants.

AMINOALKOXY-FUNCTIONAL CHALCONES

The invention provides novel alkoxyaminochalcone derivatives and analogues thereof. Use of the compounds, or compositions comprising them, as pharmaceutically active agents, in particular against bacterial and parasitic infections, is also disclosed. The