457631-44-6

Basic information

• Product Name: [4-(2-AMINO-ETHYL)-PHENYL]-CARBAMIC ACID TERT-BUTYL ESTER
• Synonyms: [4-(2-AMINO-ETHYL)-PHENYL]-CARBAMIC ACID TERT-BUTYL ESTER;tert-Butyl (4-(2-aminoethyl)phenyl)carbamate
• CAS NO: 457631-44-6
• Molecular Formula: C₁₃H₂₀N₂O₂
• Molecular Weight: 236.31
• Mol File: 457631-44-6.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: [4-(2-AMINO-ETHYL)-PHENYL]-CARBAMIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: [4-(2-AMINO-ETHYL)-PHENYL]-CARBAMIC ACID TERT-BUTYL ESTER(457631-44-6)
• EPA Substance Registry System: [4-(2-AMINO-ETHYL)-PHENYL]-CARBAMIC ACID TERT-BUTYL ESTER(457631-44-6)

Safety Data

• Hazardous Substances Data: 457631-44-6(Hazardous Substances Data)

Usage

General Description

The chemical [4-(2-amino-ethyl)-phenyl]-carbamic acid tert-butyl ester is a compound with the molecular formula C14H20N2O2. It is a carbamic acid ester, which means it is derived from the reaction between a carbamic acid and an alcohol. The tert-butyl ester group is a common protective group used in organic synthesis to prevent unwanted reactions at certain functional groups. The presence of the amine group makes this compound potentially useful in pharmaceutical research and development, as it can potentially be used as a building block for the synthesis of biologically active molecules. Additionally, the phenyl group in the molecule indicates that this compound may have some potential for applications in materials and polymer chemistry. Overall, [4-(2-amino-ethyl)-phenyl]-carbamic acid tert-butyl ester is a versatile compound with potential applications in various fields of chemistry.

Upstream product

• 13472-00-9 p-Aminophenethylamine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 40377-41-1 4-(2-(((methyl)carbonyl)amino)ethyl)aniline 
• 193204-58-9 tert-butyl N-(4-{2-[(4-methylbenzenesulfonyl)oxy]ethyl}phenyl)carbamate 
• 104060-23-3 tert-butyl N-[4-(2-hydroxyethyl)phenyl]carbamate 
• 104-10-9 2-(4'-aminophenyl)ethyl alcohol 
• 100-27-6 2-(4-nitrophenyl)ethanol 
• 3544-25-0 p-aminophenylacetonitrile 
• 140-29-4 phenylacetonitrile 
• 555-21-5 4-Nitrophenylacetonitrile 
• 1233249-35-8 4-tert-butoxycarbonylaminophenylacetonitrile 

Downstream Products

• 457631-48-0 {4-[2-(2-[1,2]dithiolan-3-yl-acetylamino)-ethyl]-phenyl}-carbamic acid tert-butyl ester 
• 223673-61-8 (R)-2-(2-aminothiazol-4-yl)-4'-[2-[(2-hydroxy-2-phenylethyl)amino]ethyl]acetanilide 
• 13472-00-9 p-Aminophenethylamine 
• 1608095-23-3 (1-{[2-(4-tert-butoxycarbonylaminophenyl)-ethylcarbamoyl]-methyl}-cyclopentyl)-acetic acid 
• 1608095-24-4 (1-{[2-(4-amino-phenyl)-ethylcarbamoyl]-methyl}-cyclopentyl)-acetic acid hydrochloride salt 
• 1608095-25-5 2-(1-(2-(4-(((9H-fluoren-9-yl)methoxy)carbonylamino)phenethylamino)-2-oxoethyl)cyclopentyl)acetic acid 
• 457631-50-4 5-[1,2]dithiolan-3-yl-pentanoic acid [2-(4-amino-phenyl)ethyl]amide 
• 457631-52-6 N-[2-(4-amino-phenyl)-ethyl]-2-[1,2]dithiolan-3-yl-acetamide 
• 457631-46-8 {4-[2-(5-[1,2]dithiolan-3-yl-pentanoylamino)-ethyl]-phenyl}-carbamic acid tert-butyl ester 

Relevant articles and documents

METHOD FOR CLEAVING AMIDE BONDS

A method for cleaving amide bonds, comprising: a) providing a molecule comprising an amide group;b) reacting the molecule comprising an amide group with hydroxylamine (NH2OH) or a salt thereof to cleave the amide bond of the amide group.

A method of preparing P ethylamine

The invention discloses a preparation method of p-aminophenylethylamine, belonging to the technical field of organic synthesis. The technical scheme is as follows: the preparation method comprises the following steps: by using p-nitrophenylethanol as a raw material, carrying out catalytic hydrogenation to reduce the para-position nitro groups of the p-nitrophenylethanol into amino groups, carrying out Boc acid anhydride protection on the para-position nitro groups, carrying out substitution reaction on hydroxy groups with sulfonyl chloride compounds to obtain sulfonic acid compounds, aminating, and finally, removing Boc groups to obtain the p-aminophenylethylamine. The preparation process is simple and easy to implement, and has the advantages of cheap and accessible raw materials, higher reaction efficiency and favorable repetitiveness.

Dynamic Covalent Assembly of Peptoid-Based Ladder Oligomers by Vernier Templating

Dynamic covalent chemistry, in conjunction with template-directed assembly, enables the fabrication of extended nanostructures that are both precise and tough. Here we demonstrate the dynamic covalent assembly of peptoid-based molecular ladders with up to 12 rungs via scandium(III)-catalyzed imine metathesis by employing the principle of Vernier templating, where small precursor units with mismatched numbers of complementary functional groups are coreacted to yield larger structures with sizes determined by the respective precursor functionalities. Owing to their monomer diversity and synthetic accessibility, sequence-specific oligopeptoids bearing dynamic covalent pendant groups were employed as precursors for molecular ladder fabrication. The generated structures were characterized using matrix-assisted laser desorption/ionization mass spectrometry and gel permeation chromatography, confirming successful molecular ladder fabrication.