4586-59-8Relevant academic research and scientific papers
Synthesis, structural assignments and antiinfective activities of 3-O-benzyl-carvotacetone and 3-hydroxy-2-isopropyl-5-methyl-p-benzoquinone
Masila, Veronica M.,Ndakala, Albert J.,Byamukama, Robert,Midiwo, Jacob O.,Kamau, Rahab W.,Wang, Mei,Kumarihamy, Mallika,Zhao, Jianping,Heydreich, Matthias,Muhammad, Ilias
, p. 3599 - 3607 (2021)
In an attempt to synthesize carvotacetone analogues, new 3-O-benzyl-carvotacetone (10) and previously reported 3-hydroxy-2-isopropyl-5-methyl-p-benzoquinone (11) were synthesized from piperitone (7). In this work, we describe the synthesis of 10 and other
Total Synthesis of (?)-Perezoperezone through an Intermolecular [5+2] Homodimerization of Hydroxy p-Quinone
Long, Yang,Ding, Yiming,Wu, Hai,Qu, Chunlei,Liang, Hong,Zhang, Min,Zhao, Xiaoli,Long, Xianwen,Wang, Shu,Puno, Pema-Tenzin,Deng, Jun
, p. 17552 - 17557 (2019/11/16)
The first copper-catalyzed intermolecular [5+2] homodimerization of hydroxy p-quinone is presented, furnishing bicyclo[3.2.1]octadienone core structures in typically good yields and excellent diastereoselectivities. Applying this synthetic approach enables a concise nine-step total synthesis of (?)-perezoperezone from commercially available 3,5-dimethoxytoluene.
