4596-57-0

Basic information

• Product Name: N-[(benzylsulfanyl)carbonothioyl]glycine
• CAS NO: 4596-57-0
• Molecular Formula: C₁₀H₁₁NO₂S₂
• Molecular Weight: 241.3298
• Mol File: 4596-57-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 420°C at 760 mmHg
• Flash Point: 207.8°C
• Density: 1.358g/cm³
• Vapor Pressure: 8.35E-08mmHg at 25°C
• Refractive Index: 1.659
• CAS DataBase Reference: N-[(benzylsulfanyl)carbonothioyl]glycine(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(benzylsulfanyl)carbonothioyl]glycine(4596-57-0)
• EPA Substance Registry System: N-[(benzylsulfanyl)carbonothioyl]glycine(4596-57-0)

Safety Data

• Hazardous Substances Data: 4596-57-0(Hazardous Substances Data)

Usage

General Description

N-[(benzylsulfanyl)carbonothioyl]glycine is a chemical compound with the molecular formula C10H11NO2S2. It is a thiol-containing amino acid derivative with potential application in the treatment of neurodegenerative diseases. It is known to exhibit antioxidant and neuroprotective properties, which may have therapeutic implications for conditions such as Alzheimer's disease and Parkinson's disease. Additionally, this compound has been studied for its potential role in preventing brain damage caused by oxidative stress and inflammation. Its specific mechanism of action and potential side effects in the human body are areas of ongoing research.

Upstream product

• 75-15-0 carbon disulfide 
• 56-23-5 tetrachloromethane 
• 60-29-7 diethyl ether 
• 100-44-7 benzyl chloride 
• 598-41-4 H-Gly-NH₂ 
• 540-61-4 2-aminoacetonitrile 
• 56-40-6 glycine 

Downstream Products

• 63140-79-4 2-benzylsulfanyl-4-((Z)-4-methyl-benzylidene)-4H-thiazol-5-one 
• 66135-03-3 2-benzylsulfanyl-4-((Z)-4-fluoro-benzylidene)-4H-thiazol-5-one 
• 63140-81-8 2-benzylsulfanyl-4-((Z)-4-chloro-benzylidene)-4H-thiazol-5-one 
• 141945-03-1 2-benzylthio-4-(2-pyrimidinylamino)methylene-5(4H)-thiazolone 
• 141945-18-8 2-benzylthio-4-phenylaminomethylene-5(4H)-oxazolone 
• 875237-98-2 2-benzylsulfanyl-4-ethoxymethylene-4H-thiazol-5-one 
• 855930-97-1 (N-benzylsulfanylcarbonyl-glycine )-acetic acid-anhydride 
• 71011-43-3 [(4-Chloro-phenylcarbamoyl)-methyl]-dithiocarbamic acid benzyl ester 

Relevant articles and documents

Amino Acid-Based Dithiocarbamates as Efficient Intermediates for Diversity-Oriented Synthesis of Thiazoles

Amino acid-based dithiocarbamates were introduced as efficient intermediates for the synthesis of a diverse library of novel di- and tri-substituted thiazoles via condensation with various reagents such as anhydrides, acyl halides, benzene sulfonyl chloride, trifluoromethanesulfonic anhydride, chloroethyl formate, and diethyl chlorophosphate. The utilities of adducts in further organic synthesis were confirmed by Sonogashira and oxidation reactions. In addition, reaction of aspartic acid-based dithiocarbamates with anhydrides affords the corresponding fused 6,6a-dihydrofuro[3,2-d]thiazol-5(3aH)-ones diastereoselectively in excellent yields.

Synthesis of a new series of dithiocarbamate-linked peptidomimetics and their application in Ugi reactions

Novel peptidomimetics containing dithiocarbamate groups were synthesized via the Ugi reaction. Also, dithiocarbamates of natural amino acids were prepared and were used successfully in Ugi reactions to prepare novel peptidomimetics bearing amino acid and dithiocarbamate groups in a single structure. In addition the prepared dithiocarbamates based on amino acids are converted to the corresponding amides.