4620-46-6

Basic information

• Product Name: Butanoic acid, 2-(benzoyloxy)-3-oxo-, ethyl ester
• Synonyms: Butanoic acid, 2-(benzoyloxy)-3-oxo-, ethyl ester
• CAS NO: 4620-46-6
• Molecular Formula: C₁₃H₁₄O₅
• Molecular Weight: 250.24726
• Mol File: 4620-46-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Butanoic acid, 2-(benzoyloxy)-3-oxo-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 2-(benzoyloxy)-3-oxo-, ethyl ester(4620-46-6)
• EPA Substance Registry System: Butanoic acid, 2-(benzoyloxy)-3-oxo-, ethyl ester(4620-46-6)

Safety Data

• Hazardous Substances Data: 4620-46-6(Hazardous Substances Data)

Usage

General Description

Butanoic acid, 2-(benzoyloxy)-3-oxo-, ethyl ester, also known as Ethyl 2-benzoyloxy-3-oxobutanoate, is a chemical compound with the molecular formula C13H14O5. It is a colorless to pale yellow liquid with a fruity odor. Butanoic acid, 2-(benzoyloxy)-3-oxo-, ethyl ester is commonly used in the flavor and fragrance industry as a flavoring agent and as a solvent for cellulose derivatives and many synthetic resins. Additionally, it is used in the production of fragrances, pharmaceuticals, and as a chemical intermediate in various organic syntheses. It should be handled and stored with care due to its potential health hazards and flammability.

Upstream product

• 2009-97-4 ethyl 2-diazo-3-oxobutanoate 
• 65-85-0 benzoic acid 
• 141-97-9 ethyl acetoacetate 
• 609-15-4 ethyl 2-chloro-3-oxo-butyrate 
• 582-25-2 Potassium benzoate 
• 532-32-1 sodium benzoate 
• 84911-18-2 ethyl 2-bromoacetoacetate 

Downstream Products

• 105631-63-8 ethyl (2R,3S)-benzoyloxy-3-hydroxybutanoate 
• 105631-62-7 ethyl (2S,3S)-benzoyloxy-3-hydroxybutanoate 
• 4620-52-4 Ethyl 4-methyl-2-phenyloxazole-5-carboxylate 
• 248924-06-3 (4-methyl-2-phenyloxazol-5-yl)methanol 
• 625106-10-7 5-chloromethyl-4-methyl-2-phenyl-oxazole 
• 137267-35-7 4-ethyl-2-phenyloxazole-5-carboxylic acid 
• 91137-55-2 4-methyl-2-phenyl-1,3-oxazole-5-carboxylic acid 

Relevant articles and documents

Rhodium-catalyzed synthesis of α-amido- and α-carboxylic- β-ketoesters

The rhodium-catalyzed N-H and O-H insertion of amides and carboxylic acids with α-diazo-β-ketoesters to give different α-amido- and α-carboxylic-β-ketoesters is presented. Investigations were carried out to establish an efficient N-H and O-H insertion reaction using a range of different amides and carboxylic acids for the synthesis of intermediates e.g. for receptor antagonists. The reactions were performed under mild conditions with 1 mol% of catalyst and the products were formed in good yields. Georg Thieme Verlag Stuttgart.

A new approach to the synthesis of 2-aryl-4-halomethyl-5-methyl-1,3- oxazoles by highly regioselective direct halogenation with NBS or NCS/MeCN

A simple and efficient method for the synthesis of 2-aryl-4-bromomethyl-5- methyl-1,3-oxazoles 2 and 2-aryl-4-chloromethyl-5-methyl-1,3-oxazoles 3 is described. The reaction of 2-aryl-4,5-dimethyl-1,3-oxazoles 1 with N-bromosuccinimide and N-chlorosuccini