46279-13-4Relevant academic research and scientific papers
Bis-phenanthroline copper(ii) phthalate complexes are potent in vitro antitumour agents with 'self-activating' metallo-nuclease and DNA binding properties
Kellett, Andrew,O'Connor, Mark,McCann, Malachy,McNamara, Mary,Lynch, Patrick,Rosair, Georgina,McKee, Vickie,Creaven, Bernie,Walsh, Maureen,McClean, Siobhan,Foltyn, Agnieszka,O'Shea, Denis,Howe, Orla,Devereux, Michael
, p. 1024 - 1027 (2011/03/16)
Three, structurally characterised, bis-phen Cu(ii) complexes of the phthalate isomers display rapid, low micromolar in vitro cytotoxicity against a range of epithelial tumour cells. The complexes induce relaxation of supercoiled plasmid DNA in the absence of external reducing agents and display efficient CT-DNA, Poly[d(A-T)]2 and Poly[d(G-C)]2 binding.
Crystal structures and electrochemical property of two novel complexes [Cu(o-phth)(H2O)]n and [Co(3-nitro-phth)(4,4′-bipy) 2(H2O)3]n
Qiao, Hai-Bin,Shen, Xiao-Qing,Zhang, Hong-Yun,Yuan, Li-Jie,Chen, Pei-Kun,Mao, Hong-Yan,Hou, Hong-Wei
, p. 627 - 632 (2008/10/09)
A copper(II) complex with o-phthalate acid [Cu(o-phth)-(H 2O)]n (1) and a cobalt(II) complex with 3-nitro-phthalic acid and 4,4′-bipyridine [Co(3-nitro-phth) (4,4′-bipy) 2(H2O)3]n (2) have been synthesized. These two novel complexes were characterized by IR, X-ray crystallography diffraction. Complex 1 belongs to monoclinic crystal with C2 (1)/c space group, the complex 2 triclinic crystal with P-1. Also, electrochemical properties of these complexes and thermal decomposition process of complex 1 were investigated. Copyright
