827-27-0

Basic information

• Product Name: PHTHALIC ACID DISODIUM SALT
• Synonyms: 1,2-Benzenedicarboxylicacid,monosodiumsalt;SODIUM PHTHALATE (NEUTRAL);SODIUM PHTHALATE;PHTHALIC ACID DISODIUM SALT;DISODIUM PHTHALATE;Phthalic acid 1-sodium salt;Phthalic acid hydrogen 1-sodium salt;Sodium Hydrogen Phthalate AR
• CAS NO: 827-27-0
• Molecular Formula: C₈H₅O₄*Na
• Molecular Weight: 210.09
• EINECS: 212-568-9
• Mol File: 827-27-0.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: PHTHALIC ACID DISODIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: PHTHALIC ACID DISODIUM SALT(827-27-0)
• EPA Substance Registry System: PHTHALIC ACID DISODIUM SALT(827-27-0)

Safety Data

• Hazardous Substances Data: 827-27-0(Hazardous Substances Data)

Usage

General Description

Phthalic Acid Disodium Salt, also known as Sodium Phthalate, is a derivative of Phthalic Acid. It can occur in either a crystalline or granulated form and is typically white in color. This chemical is used widely in industrial settings such as the manufacture of dyes, soaps, pharmaceuticals, and other chemical compounds due to its use as a buffering agent. Phthalic Acid Disodium Salt can also be used as a laboratory reagent in various scientific experiments. It is important to handle this chemical with care as there might be potential health risks associated with prolonged exposure, such as skin, eye irritation, and potential risks to the respiratory system if inhaled as a dust.

InChI:InChI=1/C8H6O4.Na/c9-7(10)5-3-1-2-4-6(5)8(11)12;/h1-4H,(H,9,10)(H,11,12);/q;+1/p-2

Synthetic route

benzene-1,2-dicarboxylic acid (88-99-3) → sodium hydrogen phthalate hemihydrate (827-27-0)

Conditions	Yield
With sodium hydrogencarbonate In water

sodium hydrogen phthalate hemihydrate (827-27-0) + chloroacetic acid ethyl ester (105-39-5) → phthaloyldioxydi-acetic acid diethyl ester (1830-13-3)

mercury(II) diacetate (1600-27-7) + sodium hydrogen phthalate hemihydrate (827-27-0) + acetic acid (64-19-7) → carbon dioxide (124-38-9) + o-hydroxomercurio-benzoic acid-anhydride

di(pyridin-2-yl)amine (1202-34-2) + sodium hydrogen phthalate hemihydrate (827-27-0) + nickel(II) nitrate → triaqua{1,2-benzenedicarboxylato(2-)}(2,2'-dipyridylamine)nickel(II) dihydrate

Conditions	Yield
With H2O In water slow evapn. from dilute aq. soln. contg. equimolar amts. of nitrate, diamine and sodium phthalate;

1,10-Phenanthroline (66-71-7) + sodium hydrogen phthalate hemihydrate (827-27-0) + cobalt(II) nitrate → {Co(C8H4O4)(C12H8N2)(H2O)3}*H2O

Conditions	Yield
With H2O In water slow evapn. from dilute aq. soln. contg. equimolar amts. of nitrate, diamine and sodium phthalate;

1,10-Phenanthroline (66-71-7) + sodium hydrogen phthalate hemihydrate (827-27-0) + nickel(II) nitrate → triaqua{1,2-benzenedicarboxylato(2-)}(1,10-phenanthroline)nickel(II)monohydrate

Conditions	Yield
With H2O In water slow evapn. from dilute aq. soln. contg. equimolar amts. of nitrate, diamine and sodium phthalate;

copper(ll) sulfate pentahydrate + ammonium molybdate + sodium hydrogen phthalate hemihydrate (827-27-0) → [29H,31H-phthalocyanine-2,9,16,23-tetrasulfonato(2-)-N29,N30,N31,N32]copper (14285-62-2)

Conditions	Yield
With NH4Cl; urea In nitrobenzene mixture ground until homogenous, added slowly to nitrobenzene while temp. maintained between 160 and 190°C, heated for further 6 h at 180°C; ground, washed with MeOH, placed in HCl satd. with NaCl, dialysed through a cellulose membrane for 6 days, filtered, concd., refluxed with EtOHfor 2 h, filtered, vacuum dried (E-3 mmHg) at room temp., UV, elem. anal.;

copper(II) choride dihydrate + sodium hydrogen phthalate hemihydrate (827-27-0) → copper(II)dihydrate-biphthalate (152203-32-2, 17855-37-7, 295350-16-2, 60243-06-3)

Conditions	Yield
In water hot soln. of Na salt (distd. H2O) poured to soln. of Cu salt in min. amt. of hot distd. H2O in stoich. ratio; cooled to room temp., ppt. filtered, washed (H2O), dried in air; elem. anal., detd. by TGA;

cobalt(II) nitrate hexahydrate + sodium hydrogen phthalate hemihydrate (827-27-0) → [cobalt(II)hexahydrate]biphthalate

Conditions	Yield
In water hot soln. of Na salt (distd. H2O) poured to soln. of Co salt in min. amt. of hot distd. H2O in stoich. ratio; cooled to room temp., ppt. filtered, washed (H2O), dried in air; elem. anal., detd. by TGA;

ferrous(II) sulfate heptahydrate + sodium hydrogen phthalate hemihydrate (827-27-0) → [iron(II)hexahydrate]biphthalate

Conditions	Yield
In water in inert atm.; hot soln. of Na salt (distd. H2O) poured to soln. of Fe salt in min. amt. of hot distd. H2O in stoich. ratio; cooled to room temp., ppt. filtered, washed (H2O), dried in air, recrystd. from H2O; elem. anal., detd. by TGA;

nickel(II) sulfate hexahydrate + sodium hydrogen phthalate hemihydrate (827-27-0) → [nickel(II)hexahydrate]biphthalate

Conditions	Yield
In water in inert atm.; hot soln. of Na salt (distd. H2O) poured to soln. of Ni salt in min. amt. of hot distd. H2O in stoich. ratio; cooled to room temp., ppt. filtered, washed (H2O), dried in air; elem. anal., detd. by TGA;

Upstream product

• 85-44-9 phthalic anhydride 
• 19336-96-0 2-((2-methoxyphenyl)carbamoyl)benzoic acid 
• 19336-93-7 N-(2'-hydroxyphenyl)phthalamic acid 
• 88-99-3 benzene-1,2-dicarboxylic acid 

Downstream Products

• 88-99-3 benzene-1,2-dicarboxylic acid 
• 523-24-0 diammonium phthalate 
• 131-17-9 diallyl phthalate 
• 724425-66-5 4-(diphenylphosphinyl)benzene-1,2-dicarbonitrile 
• 724425-61-0 ethyl (3,4-dicyanophenyl)phenylphosphinate 
• 490038-15-8 4-Bromophthalamid 
• 182296-29-3 diethyl (3,4-dicyanophenyl)phosphonate 
• 70484-01-4 4-bromo-1,2-dicyanobenzene 
• 6968-28-1 4-bromophthalic acid 
• 1830-13-3 phthaloyldioxydi-acetic acid diethyl ester 
• 7250-61-5 nickel phthalate 

Relevant articles and documents

Effect of L-Valine on the growth and characterization of Sodium Acid Phthalate (SAP) single crystals

Undoped and amino acid doped good quality single crystals of Sodium Acid Phthalate crystals (SAP) were grown by slow evaporation solution growth technique which are semiorganic in nature. The effect of amino acid (L-Valine) dopant on the growth and the properties of SAP single crystal was investigated. The single crystal X-ray diffraction studies and FT-IR studies were carried out to identify the crystal structure and the presence of functional groups in undoped and L-Valine doped SAP crystals. The transparent nature of the grown crystal was observed using UV-Visible spectrum. The thermal decomposition of the doped SAP crystals was investigated by thermo gravimetric analysis (TGA) and differential thermal analysis (DTA). The enhancement in the NLO property of the undoped and L-Valine doped SAP crystals using KDP crystal as a reference was studied using SHG measurements. Vickers micro hardness measurements are used for the study of mechanical strength of the grown crystals.

Preparation method of water phase synthesized diallyl phthalate

The invention relates to the field of organic compound preparation methods, particularly to a preparation method of water phase synthesized diallyl phthalate. The method comprises the following steps:(1) preparing salt; (2) esterifying; (3) neutralizing and washing with water; (4) performing pressure-reduced distillation.

Kinetics and mechanism of hydrolysis of N-(2′-hydroxyphenyl) phthalamic acid (1) and N-(2′-methoxyphenyl)phthalamic acid (2) in a highly alkaline medium

A kinetic study on hydrolysis of N-(2′-hydroxyphenyl)phthalamic acid (1), N-(2′-methoxyphenyl)phthalamic acid (2), and N-(2′- methoxyphenyl)benzamide (3) under a highly alkaline medium gives second-order rate constants, kOH, for the reactions o